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WHAT AMLODIGAMMA IS AND WHAT IT IS USED FOR
Amlodipine contains the active substance amlodipine, which belongs to a group of medicinal products known as calcium antagonists.
They are used to treat high blood pressure (hypertension), or a certain type of chest pain called angina (angina), rare in which is Princeton's angina or so-called angina pectoris. variant angina.
For patients with high blood pressure, the medicine works by relaxing the walls of the blood vessels so that blood passes through them. In patients with angina pectoris, Amlodigmma works by improving the blood supply to the heart muscle, which thus gets more oxygen and as a result, prevents chest pain. This medicine does not provide rapid relief of chest pain in angina.
2. BEFORE YOU TAKE AMLODIGAMMA
Do not take Amlodigamma:
if you are allergic (hypersensitive) to amlodipine, to any of the other ingredients of the medicine listed in section 6 or to other calcium antagonists. This may be pain, reddening of the skin or difficulty in breathing;
if you have very low blood pressure (hypotension);
if you have a narrowing of the aortic heart valve (aortic stenosis) or a cardiogenic shock (a condition where the heart fails to supply the body with enough blood);
if you suffer from heart failure after a heart attack.
Take special care with Amlodigamma
You should tell your doctor if you have or have had any of the following conditions:
A recent heart attack;
Serious increase in blood pressure (hypertensive crisis);
If you are elderly and your dose should be increased.
Use in children and adolescents
There are no studies of Amlodipine in children less than 6 years of age. Amlodipine should only be used in children and adolescents aged 6 to 17 years (see section 3).
For more information, contact your doctor.
Taking other medicines
Please tell your doctor or pharmacist if you have taken or are currently taking other medicines, including medicines obtained without a prescription.
Amlodipine may be affected or affected by other medicinal products, such as:
Ketoconazole, intraconazole (antifungal medicinal products);
Ritonavir, indinavir, nelfinavir (so-called protease inhibitors used to treat AIDS);
Rifampicin, erythromycin, clarithromycin (antibiotics);
Hypericum perforatum (St. John's wort);
Verapamil, diltiazem (medicinal products for heart disease);
Dannrol (infusion used in severe temperature conditions);
Simvastatin (a cholesterol lowering drug).
Amlodipine may lower your blood pressure even more if you already take other medicines to treat high blood pressure.
Taking Amlodigamma with food and drink
Patients who take Amlodigamma should not consume grapefruit or grapefruit juice, because grapefruit and grapefruit juice can lead to an increase in the blood levels of the active substance amlodipine, which unpredictably increases the blood pressure lowering effect of Amlodiphamma.
The safety of amlodipine in human pregnancy has not been established. If you think you are pregnant or plan to become pregnant, you should tell your doctor before you start taking Amlodipine.
It is not known whether Amlodipine passes into breast milk. If you are breast-feeding or breast-feeding, you should tell your doctor before taking Amlodipine.
Ask your doctor or pharmacist for advice before taking any medicine.
Driving and using machines
Amlodipine may affect your ability to drive and use machines. If you feel sick, dizzy or tired from your tablets, or if you get a headache, you should not drive or operate machines, but you should contact your doctor immediately.
Important information about other ingredients of Amlodigamma tablets
3. HOW TO TAKE AMLODIGAMMA
Always take your medicine exactly as prescribed by your doctor. Consult your doctor or pharmacist if you are not sure about anything.
The usual starting dose is 5 mg Amlodipine once daily. The dose may be increased to 10 mg Amlodipine once daily.
You can take your medicine before or after eating and drinking. You should take your medicine every day, at the same time, with a glass of water.
Do not take Amidigamma tablets with grapefruit juice.
Use in children and adolescents
The recommended usual starting dose in children and adolescents (aged 6-17 years) is 2.5 mg per day. The maximum recommended dose is 5 mg per day.
Amlodipine tablets of 2.5 mg are not available and the 2.5 mg dose can not be obtained from the 5 mg tablet because the tablets
If you stop taking Amlodigamma
Your doctor will advise you on how long you should take your medicine. Your condition may get worse if you suddenly stop taking Amlodigamma before you are advised to do so.
If you have any further questions, ask your doctor or pharmacist.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Amlodipine 10 mg tablets can cause side effects, although they do not occur in any patient.
Visit your doctor immediately if you experience any of the following very rare, serious side effects after taking this medicine:
sudden chest pain, chest pain, shortness of breath, or difficulty in breathing;
swelling of the eyelids, face or lips;
swelling of the tongue and throat, which causes great difficulty in breathing;
severe skin reactions, including massive skin rash, urticaria, redness of the skin throughout the body, severe itching, blistering of the skin, peeling and swelling of the skin, mucosal irritation (Stevens Johnson syndrome) or other allergic reactions;
cardiac infarction, arrhythmia;
inflammation of the pancreas, which can cause very severe abdominal pain and back pain.
The following common side effects have been reported. If any of these issues disturb you or continue to occur for more than a week, you should contact your doctor.
Common (affects 1 to 10 users in 100):
Headache, vertigo, drowsiness (especially at the beginning of treatment);
Palpitations (sensation of heart attacks), redness;
Abdominal pain, vomiting (nausea);
Swelling of the ankles (edema), fatigue.
The following list includes other side effects that have been reported.
If any of the side effects gets serious, or if you notice a reaction not listed in this leaflet, please tell your doctor or pharmacist.
Uncommon (affects 1 to 10 users in 1,000):
mood swings, depression, anxiety, drowsiness;
uncontrolled trembling, changes in taste, seizures, feeling weak / tired;
numbness or tingling sensation in the limbs, reduced sensation for pain sensation, visual disturbances, double vision, tinnitus;
decreased blood pressure;
sneezing / runny nose, due to inflammation of the lining of the nose (rhinitis);
changes in the usual intestinal peristalsis, diarrhea, constipation, indigestion, dry mouth, vomiting;
hair loss, increased sweating, itchy skin, red spots on the skin, discoloration of the skin;
urinary incontinence, increased night urination, increased urinary frequency;
inability to get an erection, discomfort or breast enlargement in men;
weakness, pain, feeling unwell;
joint or muscle pain, muscle cramps, back pain;
increasing or decreasing body weight.
Rare (affects 1 to 10 users in 10,000):
a sense of confusion.
Very rare (affects less than 1 user in 10,000):
decreased number of white blood cells, decreased platelet counts, which may lead to unusual bruising or bleeding (damage to red blood cells);
increased blood sugar (hyperglycaemia);
a nerve disorder that may lead to weakness, numbness or tingling;
cough, swelling of the gums;
abdominal swelling (gastritis);
liver function disorder, hepatic inflammation (hepatitis), yellowing of the skin (jaundice), elevation of liver enzymes which may have an effect on some medical tests;
increased tension in muscles;
inflammation of the blood vessels, often with skin rash;
sensitivity to light;
disturbances that combine rigidity, tremor and / or motor impairment Communication of side effects.
HOW TO STORE AMLODIGAMMA
Keep out of the reach and sight of children.
Do not use Amlodipine after the expiry date which is stated on the carton or blister after EXP. Expiry date is the last day of the indicated month.
Store below 25 ° C. Store in the original package in order to protect from moisture.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of your unnecessary medicines. These measures will help to protect the environment.
6. ADDITIONAL INFORMATION
What Amlidigamma contains
The active substance is amlodipine.
Each tablet contains 10 mg of amlodipine (as besylate).
Excipients: povidone K 30, microcrystalline cellulose (E460), anhydrous calcium hydrogen phosphate (E341), crospovidone, magnesium stearate (E470b).
What Amlodigamma tablets look like and contents of the pack
Amidigamma 10 mg tablets are white, round, biconvex, scored on both sides. The tablets can be divided into two equal halves.
The tablets are packed in blister packs in cartons containing 14, 20, 30, 50 and 100 tablets.
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