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What is Cusimolol * 0.5% eye drops and what is it used for?
CUSIMOLOL 0.5% eye drops are for the treatment of elevated intraocular pressure. Such pressure can cause a disease called glaucoma.
High pressure in the eye. Your eye contains a transparent, watery liquid that nourishes the inside of the eye. This liquid is thrown out of the eye and at the same time a new one is produced. If the eye is filled with fluid faster than it is empty, the pressure inside the eye increases. If the pressure rises too much, it can cause visual impairment.
Cuzimolol 0.5% eye drops is a representative of a group of medicines to treat glaucoma called beta-blockers. It works by reducing the production of fluid inside the eye and thus reducing intraocular pressure. It can be used alone or together with other topical medicines that also lower the pressure.
2. What you need to know before you use CUSIMOLOL 0.5% eye drops
Do not use Kuzimolol 0.5% eye drops:
if you are allergic to timolol, beta-blockers or any of the other ingredients of this medicine (listed in section 6).
if you have or have had a history of breathing problems such as asthma, severe chronic obstructive bronchitis (a severe lung condition that may cause swirling breathing, shortness of breath and / or prolonged cough) if you have delayed heartbeat, heart failure or heart rhythm.
Warnings and precautions
Talk to your doctor or pharmacist before using 0.5% eye drops of CuSIMIOLOL.
• Use this medicine only for dropping in your eyes.
Before using this medicine, tell your doctor if you have or have had a history of:
• coronary heart disease (symptoms may include chest pain, shortness of breath or asphyxia), heart failure, low blood pressure
• heart disorders such as slow heartbeat
• respiratory problems, asthma or chronic obstructive pulmonary disease
• a disease with reduced blood circulation (such as Raynaud's disease or Raynaud's syndrome)
• diabetes, as timolol may mask the signs and symptoms of low blood sugar
• increased activity of the thyroid gland since timolol may mask signs and symptoms
• if you have a myasthenia gravis (chronic neuromuscular weakness) or other muscle weakness
• if you have corneal disease, talk to your doctor because CUSIMOLOL 0.5% eye drops may cause dry eye
Prior to surgery, tell your doctor that you are taking CYP3AXA 0.5% eye drops as timolol may alter the effects of some medicines used during anesthesia.
If you get any serious allergic reaction (skin rash, redness or pruritus in your eye) while you are taking KUMIMINOL 0.5% eye drops, whatever the cause, adrenaline treatment may not be effective. Therefore, if you are using any other treatment, tell your doctor that you are using Kuzimolol 0.5% eye drops.
In the pediatric population:
CUSIMOLOL 0.5% eye drops should be used with caution in young patients. In neonates, infants and young children, CUSIMOLOL 0.5% eye drops should be used with extreme caution. The medicine should be stopped immediately if cough, wheezing (chest chest), abnormal breathing or abnormal breathing pauses (apnea) occur. Contact your doctor as soon as possible. A portable apnea monitor can also be useful.
Timelol data has been accumulated in studies with children aged 12 to 5 years who have had elevated eye / eye pressure or who have been diagnosed with glaucoma. Contact your doctor for more information.
Tell your doctor before you start taking this medicine:
• If you have untreated phaeochromocytoma (adrenal adenocarcinoma)
• If you have excessive blood acidity (a condition called metabolic acidosis)
• If you take other medicines. Please also read the section "Other medicines and Cuizimol 0.5% eye drops"
Other medicines and Kuzimolol 0.5% eye drops
KUSIMOLOL 0.5% eye drops may affect or be affected by other medicines you are taking, including other eye drops, to treat glaucoma. Tell your doctor if you are taking or intend to take medicines for lowering your blood pressure, heart medicines, including quinidine (used to treat heart disease and some types of malaria), diabetes medicines or antidepressants known as fluoxetine and paroxetine.
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Pregnancy, breastfeeding and fertility
If you are pregnant or are breast-feeding, think you may be pregnant or plan to become pregnant, ask your doctor or pharmacist for advice before taking this medicine.
Do not use CUSIMOLOL 0.5%
Do not use Cusimol 0.5% eye drops if you are breast-feeding, timolol may pass into breast milk. Ask your doctor before taking any medicine during breast-feeding.
Driving and using machines
It is possible to detect short-term vision blur after using 0.5% eye drops of CuZimilol. Do not drive or operate machinery until your vision is clear.
CUSIMOLOL 0.5% eye drops contain benzalkonium chloride
If you wear contact lenses do not use the medicine while the lenses are in the eyes, wait 15 minutes after using eye drops before putting the contact lenses back. KUSIMOLOL 0.5% eye drops contain a preservative (benzalkonium chloride) that can cause irritation and discolour your soft contact lenses.
3. How to use Cuzimol 0.5% eye drops?
Always use this medicine exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist.
Use CUSIMOLOL 0.5% eye drops only for eye drops in your eye / eyes.
Adults: 1 drop in the affected eye (s) twice a day.
In some specific cases, the doctor will determine the dosage.
In some cases, it may be necessary to use 0.5% eye drops of CuSIMOLOL together with other medicines.
Extensive medical examination should be made prior to the use of 0.5 mg eye drops of CuZimilol. Your doctor will carefully evaluate the risks and benefits of treatment with KUSIMOLOL 0.5% eye drops. If the benefit outweighs the risk, it is recommended to use the lowest available drug concentration once daily. For "use in children", a 0.1% drug concentration may be considered appropriate to control the pressure in the eye.
If intraocular pressure (IOP) can not be sufficiently controlled with this dose, a careful increase may be made twice a day, with a 12-hour interval. In addition, patients, especially newborns, should be closely monitored after the first dose for one to two hours (in the office) and monitored for ocular and systemic side effects until surgery has been performed.
One drop a day in the affected eye / eye - as often as determined by the doctor.
After eye dropping the eye (s) should be kept as closed for as long as possible (3-5 minutes) and the corner of the eye closest to the nose should be pressed to prevent the proliferation of KUSIMOLOL 0.5% eye drops in the body.
Duration of treatment:
For short-term use in pediatric patients.
Use Kuzimolol 0.5% eye drops for both eyes only if your doctor tells you to.
Your doctor will determine how long you should use CuZimilol 0.5% eye drops. Do not stop treatment too soon.
1. Take the bottle with Kuzimolol 0.5% eye drops and a mirror.
2. Wash your hands.
3. Unscrew the cap.
4. Keep the bottle pointing down between your thumb and fingers (Figure 1).
5. Tilt your head backwards. Repeat the eyelid, with the fingers already cleaned, so as to form a "pocket" between it and the eye. The drop will fall exactly at this point (Figure 2).
6. Close the tip of the bottle near the eye. Use the mirror if it will make it easier for you.
7. Be careful not to touch the eye, eyelids, surrounding area or other surfaces with the tip of the applicator-dropper. There is a danger of the drops being dirty.
8. Gently push the base of the bottle to drop one drop of 0.5% CuZIMILOL (Figure 3).
9. Once you have placed Kuzimol 0.5%, close the eyelid and press the eye with your finger in the corner at the nose (Figure 4) for 2 minutes. This will prevent Cuzimol 0.5% from going to other parts of the body.
10. If you have to use the drops on both eyes, repeat the previous steps for the other eye.
Close the bottle well immediately after use.
Do not open a new bottle until you've used the first bottle.
How much to use:
If the drop does not fall into the eye, try again.
If you use more than the required amount of KUSIMOLOL 0.5% eye drops, immediately rinse with warm water. Do not put more drops until the time comes for the next regular dose.
If you forget to use 0.5% eye drops of CuSIMIOLOL, continue with the next dose according to your usual schedule. However, if it is time for your next dose, skip the missed dose and switch to your usual dosage regimen. Do not put a double dose to make up for the missed dose.
If you stop using CUSIMIOL 0.5% eye drops without your doctor's agreement, the pressure in your eye will not be controlled and this may lead to loss of vision.
Stop using 0.5% eye drops and ask your doctor if you have: slow heartbeat, breathing or heart problems, dizziness or headache.
If you use other ophthalmic products, wait five minutes between insertion
Reactions of unknown frequency (can not be estimated from the available data)
Eye side effects: Eyelid anemia.
Additional side effects identified in post-marketing surveillance that have been reported, the frequency of which can not be estimated from the available data:
Effects in the eye: separation of the lower blood layer under the retina after filtration surgery, which may cause visual disturbance; fall of the upper eyelid (the eye remains half closed).
General effects: swelling under the skin that occurs in the areas of the face and extremities and may obstruct the airways and make it difficult to swallow, allergy, low blood glucose levels, insomnia, memory loss, nightmares, stroke, fainting, abnormal sensations such as needle pricking, heart attack, heart rhythm disturbance, aggravated congestive heart failure (heart disease with shortness of breath and swelling of the feet and feet due to fluid build-up), changes in heart rhythm or frequency, palpitations, Raynaud's phenomenon, vomiting, diarrhea, nausea, hives or rash with itching, psoriasis, rash, hair loss, joint disease (or joint damage), sexual dysfunction.
Like other medicines used in the eyes, timolol is absorbed into the blood. This can cause similar side effects to those seen with intravenous and / or oral beta-blockers. The incidence of adverse reactions after topical ocular administration is lower than that of oral or injectable medication. The listed side effects include those typical of the beta-blocker class when used to treat ocular conditions:
Eye irritation: irritation (eg burning, stinging, itching, tearing, redness), inflammation of the eyelid, corneal inflammation, blurred vision and peeling of the blood-containing layer under the retina after filtration surgery, which may cause visual disturbances corneal sensation, dry eyes, erosion of the cornea (damage to the front layer of the eyeball), fall of the upper eyelid (a condition where the eye remains half closed), double vision.
General side effects: allergic reactions including swelling under the skin (this may occur in areas such as the face and extremities and may narrow the airway, which may cause difficulty in swallowing and breathing), hives (or rash with itching ), localized and common rash, pruritus, severe, sudden, life-threatening allergic reaction.
- Low blood glucose levels.
- Difficulties with sleep (insomnia), depression, nightmares, memory loss.
- Loss of consciousness, stroke, decreased blood supply to the brain, increased signs and symptoms of myasthenia gravis (muscle disorders), dizziness, abnormal sensations (such as needle-sticking) and headache.
- Delayed heart rate, chest pain, palpitations, swelling (fluid build-up), changes in heart rhythm or frequency, congestive heart failure (heart disease with shortness of breath and swelling of the feet and feet due to fluid build-up) heart rhythm, heart attack, heart failure.
- Low blood pressure, Raynaud's phenomenon, cold hands and legs.
- Collapse of the respiratory tract in the lungs (mainly in patients with an existing disease), difficulty in breathing, cough.
- Disorders of taste, nausea, indigestion, diarrhea, dry mouth, stomach pain, vomiting.
- Hair loss, rash with white silver staining (psoriasiform rash) or worsening of psoriasis, skin rash.
- Muscle pain that is not caused by physical exercise.
- Disturbed sexual function, reduced libido.
- Muscle weakness / fatigue.
In very rare cases, some patients with severe damage to the transparent layer at the front of the eye (cornea) develop cloudy spots on the cornea due to calcium accumulations during treatment.
How to store Cuzimol 0.5% eye drops?
Keep out of the reach and sight of children.
Do not use this medicine after the expiry date which is stated on the bottle and carton after EXP. The expiry date refers to the last day of that month.
Store below 25 ° C.
The bottle should be discarded 4 weeks after the first opening to avoid possible infections and you need to start a new bottle.
Do not dispose of medicines in the sewage system or in the household waste container. Ask your pharmacist how to dispose of medicines you no longer use, and these measures will help to protect the environment.
6. Contents of the package in additional information
What Cuzimolol contains 0.5% eye drops:
The active substance is timolol (such as timolol maleate) 5 mg / ml.
The other ingredients are: benzalkonium chloride, sodium chloride, sodium phosphate, disodium phosphate and purified water.
What does Cuzimol 0.5% look like and what does the package contain?
CUSIMOLOL 0.5% eye drops are liquid (clear, colorless solution) and are supplied in a pack containing a 5 ml plastic bottle with a screw cap.
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