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LUCETAM 200 mg. / 5 ml. 10 ampoules

Brand: EGIS
Product Code: LUCETAM 200 mg. / 5 ml. 10 ampoules
Availability: In Stock
Product viewed: 967

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WHAT IS LUCETAM AND WHAT TO USE?
The drug Piracetam, of Lucetam is nootropno (increasing cognitive and memory functions of the brain) with sophisticated drug mechanism of action.

Applications:
Adults:
• Treatment of manifestations in psycho-organic syndrome, such as: memory disorders, the inability to concentration, lack of motivation;
• Treatment of effects of ischemic (impaired blood supply due to brain), cerebrovascular accidents, in particular-aphasia (loss of speech);
. Treatment of cortical myoclonus (sudden involuntary muscle contractions), as samostâtelno treatment or in combination;
• Treatment of Vertigo (dizziness) and related disorders of balance, with the exception of lightheadedness from vascular or psychic origin.
Children:
• Treatment of dizleksiâ (disturbances in the ability to read) in combination with other appropriate therapeutic approaches, such as speech therapy.


BEFORE YOU CAN START USING LUCETAM
Contraindications:
-hypersensitivity (allergy) to the drug or the excipients;
severe renal insufficiency (glumerulna filtration under 20 ml/min);
-hemorrhagic stroke (bleeding in the brain, stroke);
-pregnancy or breastfeeding because the drug passes through the placenta and breast milk.

Particular attention must be paid to the following:
In kidney damage, the drug should be taken in lower doses and renal function should regularly be tested (see item 3). In the elderly this research needs to be done before the beginning of treatment. In patients with epilepsy and those prone to muscle spasms, the drug can provoke seizures. Antikonvulsivnata therapy (treatment for seizures) should be carefully reviewed by a specialist doctor, even with a significant improvement of the situation, resulting from the adoption of piracetam. Due to suppressing effect on platelet aggregation (agglutination of platelets and the kr″vospiraneto) requires special attention when the drug is given to patients with impaired Haemostatic clamps, or heavy bleeding after surgery. Patients treated for cortical myoclonus abrupt cessation of treatment may lead to sudden deterioration or a new attack.

Pregnancy and lactation
This medication is contraindicated during pregnancy and lactation. Driving and working with mašiniNâma clinical observations that piracetam responds these activities, but given the possible adverse reactions, this possibility cannot be excluded. Therefore, the extent of any ban/restriction will be determined individually by lekuvaŝšâ doctor.
Acceptance of other drugs during treatment with Lucetam
In combination of Lucetam with the following drugs should be given to the following:
-CNS stimulant (increases the incentive effect)
-Neuroleptics (increasing the increased motor activity)
-thyroid hormones (can amplify the Central effects, such as tremors, anxiety, sleep disorders, razdraznimost and confusion)
-acenocumarol (piracetam amplified its effects: significant inhibition of adhesion platelets, reduction of plasma Fibrinogen, suppression of blood coagulation, blood and plasma)
-the simultaneous use of alcohol does not affect plasma levels of piracetam and vice versa-plasma is unaffected by alcohol 1.6 g piracetam daily.

3. HOW to USE LUCETAM
The dose is determined individually depending on the severity of the disease and the clinical result. Ampoules are applied when the adoption by mouth is impossible (difficulty swallowing, unconscious). Lucetam ampoules should be administered by intravenous drip slowly, placed in one of the following solutions:
Glucose 5%, 10%, 20% Fructose 5%, 10%, 20% Levulose 5% sodium chloride 0.9% dextran Compoung 40.10% in 0.9% NaCl, 6% dextran Compoung 100 in 0.9% NaCl RingerRinger laktatManitol-DekstranHAES sterile solution 6%. So prepared solution of piracetam for infusion is fit to the 24th hour as intravenous injection medicinal product shall be administered slowly (a few minutes), diluted or undiluted. Recommended daily dose can be divided into 2-4 equal reception. The duration of the treatment depends on the clinical picture. For chronic diseases, it is necessary to continue the treatment for at least 6-12 weeks to receive optimal treatment results. After 3 months of treatment, it is necessary to review the treatment and to decide whether to continue it. If you need longer treatment recommended dose reduction or complete cessation of treatment, which is done at 6-month intervals. Depending on the causes of the disease and if good results are observed, the treatment may last for several months.

Recommended daily doses depending on readings:

Treatment of manifestations of psycho-organic syndrome: 2.4-4.8 g/day, divided into 2-3 reception. Treatment of the consequences of cerebrovascular accidents, in particular-aphasia (loss of speech): ' in the sub-acute and chronic (bonding more than 15 days) these recommended daily dose is 4.8-6 g. treatment of myoclonus: the recommended starting dose is 7.2 g per day, which can be increased to 4.8 g daily for 3-4 day intervals up to a maximum of 24 g daily. Later, depending on the improvement, recommended gradually reducing the dose every 2 days (or 3-4 days when Lance-Adams syndrome) with 1.2 g to avoid a relapse or the occurrence of seizures. Other drugs for the treatment of myoclonus can be applied in their normal dosages, as later, depending on the improvement their doses may also be reduced. The treatment of Vertigo (Vertigo): 2.4-4.8 g/day, divided into 2-3 reception. The treatment of dizleksiâ (impossible to read): the recommended daily intake in children over 8 years and adolescents is 3.2 g, divided into two reception. Dosage in the elderly : in patients with impaired renal function is recommended a reduction in the daily dose (see Dosage in renal insufficiency below). Continued treatment in elderly patients require periodic follow-up of klir′nsa (purification of the blood) creatinine. Changing the dose, if necessary, on the basis of these values. Dosage in patients with impaired hepatic function: in patients with impaired liver function is not necessary to reduce the dose. In patients with liver and kidney disease, however which comes with necessary (see Dosage in renal insufficiency below). Dosage in patients with renal failure: when such patients daily dose depends on the degree of renal failure.
Creatinine clearance (ml/min) can be determined using the following formula based on the value of serum creatinine (mg/dl):
{140-age (years)} x body weight (kg)}
BTS =-(x 0.85 in women)
72 x serum creatinine (mg/dl)

Overdose
The drug is not toxic, even if given in high doses. Pirecatem there is no specific antidote (antidote), so the possible overdose is treated with total treatment. Piracetam is subject to dialysis (purification with artificial kidney) as a pure 50-60%.
4. possible SIDE EFFECTS
Most of the following side effects occur in elderly patients and/or daily doses of 2400 mg and more:
From the CNS: nervousness (1.13%), razdraznimost, anxiety, ažitacii (excitable), aggressive behavior, sleep disorders, hyperstimulation (hyper reaction) and hiperkineziâ (increased physical activity) (1.72%)
Gastrointestinal: uncommon: nausea and vomiting, diarrhea and abdominal pain. Complaints such as high and low blood pressure, dizziness, headache, tremor, increased sexuality and allergic reactions have been reported rarely. Paradoxical reactions such as somnolentnost (drowsiness) (0.96%) and tiredness (0.23%) be observed in single cases. All the above reactions resolve to gradually reduce the dose.
5. storage of LUCETAM AMPOULES
Keep ampoules of the reach of children. Store below 25 ° c. the expiration date is printed on the carton. You should not use ampoules after that date.

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