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What is Aripipa and what it is used
Aripipa contains the active substance aripiprazole and belongs to the group of medicines called antipsychotics. It is used to treat adults and adolescents aged 15 years, suffering from a disease characterized by symptoms such as hearing, seeing or feeling things that are not there, suspiciousness, mistaken beliefs, (unbound) speech and behavior and boredom. People with this condition may experience depression experience feelings of guilt, anxiety or stress.
Aripipa is used to treat adults and adolescents aged 13 years who suffer from a disease characterized by symptoms such as feeling of elation, excessive amounts, needing much less sleep than usual, talking very quickly with racing ideas and sometimes severe irritability. In adults, it also prevents the resumption of these symptoms in patients who responded to treatment with Aripipa.
2. What you need to know before taking Aripipa
Do not take Aripipa:
• if you are allergic to aripiprazole or any of the other ingredients of this medicine (listed in section 6).
Warnings and Precautions
Talk to your doctor before taking Aripipa if you suffer from:
• high blood sugar (characterized by symptoms such as excessive thirst, excessive amounts of urine, increased appetite, feeling of weakness), or have a history of diabetes in the family;
• involuntary, irregular muscle movements, especially of the face;
• cardiovascular disease, history of cardiovascular disease in the family, stroke or "mini" stroke, abnormal blood pressure;
• the existence of blood clots, or family history of such as antipsychotics have been associated with formation of blood clots;
• strong attraction to gambling in the past.
If you notice weight gain, develop abnormal movements, experiencing somnolence, interfering with your normal daily activities, have difficulty swallowing or allergic symptoms, please tell your doctor.
If you are an elderly patient suffering from dementia (loss of memory and other mental abilities), you or your relative should tell your doctor if you have had a stroke or "mini" stroke.
Tell your doctor immediately if you have any thoughts or feelings about hurting yourself. There have been a manifestation of thoughts and suicide attempts during aripiprazole treatment.
Tell your doctor immediately if you suffer from muscle stiffness or inflexibility, accompanied by fever, sweating, altered mental status, or very rapid or irregular heartbeat.
Children and adolescents
Aripipa not be used in children and adolescents under 13 years. Ask your doctor or pharmacist before taking Aripipa.
Other medicines and Aripipa
Tell your doctor or pharmacist if you are taking, you have recently taken or might take any other medicines.
Blood pressure lowering drugs
Aripipa can increase the effect of the drugs used to lower blood pressure. Make sure your doctor knows you are taking medications to control blood pressure.
The adoption of Aripipa with other medicines may require a change in dosage.
Especially important it is to inform the doctor about the following medications:
• Medicines to correct heart rhythm
• Antidepressants or herbal remedy used to treat depression and anxiety;
• Some drugs for the treatment of HIV infection;
• Anticonvulsants used to treat epilepsy.
Drugs that increase the level of serotonin: triptans, tramadol, tryptophan, SSRI (for example paroxetine and fluoxetine), tricyclic antidepressants (e.g. clomipramine, amitriptyline), pethidine, St John's Wort and venlafaxine. Since these drugs increase the risk of side effects if you get any unusual symptom when taking any of these medicines in combination with Aripipa, consult your doctor.
Aripipa with food, beverages and alcohol
Aripipa can be taken regardless of diet (with or without food).
Alcohol should be avoided during treatment with Aripipa.
Pregnancy, lactation and fertility
If you are pregnant or breast-feeding, you think you may be pregnant or planning to become pregnant, talk to your doctor before taking this medicine.
The following symptoms can occur in infants whose mothers used Aripipa in the last trimester (last three months of pregnancy): shaking, muscle stiffness and / or weakness, sleepiness, agitation, breathing problems, and difficulty in feeding. If your baby develops any of these symptoms contact your doctor.
Breastfeeding tell your doctor immediately.
If you take Aripipa should not breastfeed.
Driving and using machines
Do not drive or use any tools or machinery until you know how you affect
Aripipa contains lactose
If your doctor has told you have an intolerance to some sugars, contact your doctor before taking this medicine.
3. How to take Aripipa
Always take this medicine exactly as you have been told by your doctor or pharmacist. If you're not sure, ask your doctor or pharmacist.
The recommended adult dose is 15 mg once daily. However, your doctor may prescribe a lower or higher dose to a maximum of 30 mg once daily.
Use in children and adolescents
Aripiprazole may initially be administered at lower doses, such as oral solution. The dosage may gradually be increased to 10 mg per day, which is the recommended dose for adolescents.
Your doctor may prescribe a lower or higher dose to a maximum of 30 mg daily.
If you think the effect of Aripipa is too strong or too weak, discuss it with your doctor or pharmacist.
Try to take Aripipa tablets at the same time each day. It does not matter whether you take them with or without food. Always take the tablets whole with water.
Even if you feel better, do not change dose Aripipa or stop treatment without first you have consulted your doctor.
If you take more than the amount Aripipa
If you find that you have taken more tablets Aripipa than prescribed (or if someone else has taken your tablets Aripipa), immediately contact your doctor. If you can not find it, go to the nearest hospital and carry a medicine pack.
If you forget to take Aripipa
If you miss a dose, take it as soon as you remember but do not take two doses in one day.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
As with all drugs, this drug may cause side effects, although not everyone gets them.
Common side effects (may affect up to 1 in 10 patients):
uncontrolled twitching or jerking movements, headache, fatigue, nausea, vomiting, discomfort in the stomach, constipation, increased salivation, dizziness, trouble sleeping, restlessness, feeling anxious, sleepiness, shaking and blurred vision.
Uncommon side effects (may affect up to 1 in 100):
some patients may feel dizzy, especially when getting up from a lying or sitting position, or fast heart rate, or double vision.
Some patients may feel depressed. Some people may experience altered or increased sexual interest.
The following adverse events were reported during the marketing of Aripipa, but their frequency is unknown (frequency can not be estimated from the available data):
Changes in the levels of some blood cells; unusual heart beat, sudden unexplained death, heart attack; allergic reaction (eg. swelling of the mouth, tongue, face and throat, itching, rash); high blood sugar, onset or worsening of diabetes, ketoacidosis (ketones in the blood and urine) or coma, low sodium level in the blood; weight gain, weight loss, anorexia; nervousness, agitation, feelings of anxiety, a passion for gambling; suicidal thoughts, suicide attempt and suicide; speech disorder, seizure, serotonin syndrome (a reaction that can cause a feeling of excessive happiness, drowsiness, clumsiness, restlessness, feeling of being drunk, fever, sweating or stiffness in muscles), a combination of fever, muscle ckovanost, rapid breathing, sweating , reduced consciousness and sudden changes in blood pressure and heart rate; fainting, high blood pressure, formation of blood clots in the veins especially in the legs (symptoms include swelling, pain and browning, which can reach the lungs and cause chest pain and difficulty breathing (in the presence of these symptoms contact doctor immediately); muscle spasm of the larynx, accidental inhalation of food with risk of pneumonia, difficulty swallowing, inflammation of the pancreas, liver failure, inflammation of the liver, yellowing of the skin and whites of the eyes, Abnormal test values of the liver, abdominal and stomach discomfort, diarrhea, skin rash and sensitivity to light, unusual hair loss or thinning, excessive sweating; stiffness or cramps, muscle pain, weakness, urinary incontinence, dysuria ; prolonged and / or painful erection, difficulties in controlling the body temperature or overheating, chest pain, and swelling of hands, ankles or feet.
In elderly patients with dementia reported more fatalities while taking aripiprazole. It is further reported cases of stroke or "mini" stroke.
Additional side effects in children and adolescents
Adverse reactions in adolescents
How to store Aripipa
Keep out of reach of children.
Do not use this medicine after the expiry date stated on the blister and carton. The expiry date refers to the last day of that month.
In order to protect from moisture store in the original packaging.
Do not dispose of medications in wastewater or household waste.
Ask your pharmacist how to dispose of medicines no longer use.
These measures will help to protect the environment.
6. Contents of the pack and other information
• The active substance is aripiprazole. Each tablet contains 15 mg of aripiprazole.
• The other ingredients are lactose monohydrate, maize starch, microcrystalline cellulose, hydroxypropyl cellulose, crospovidone, colloidal silicon dioxide, magnesium stearate, iron oxide yellow (E 172).
Aripipa looks like and contents of the pack
Tablets Aripipa 15 mg tablets are round and yellow uncoated tablets embossed with the designation "253" on one side and smooth on the other side. They are available in blister packed in cartons containing 28 and 30 tablets.
Not all pack sizes may be marketed.
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