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What is Candecard H and what it is used for
The name of your medicine is Candardard N. It is used to treat high blood pressure (hypertension) in adults. It contains two active ingredients: candesartan cilexetil and hydrochlorothiazide. They work together to lower blood pressure.
Candesartan cilexetil belongs to a group of medicines known as angiotensin II receptor antagonists. It causes relaxation and expansion of the blood vessels. This helps reduce your blood pressure;
Hydrochlorothiazide belongs to a group of medicines called diuretics (drainage tablets). It helps the body to get rid of water and salts, such as sodium in the urine. This helps reduce blood pressure.
Your doctor may prescribe Candecard H if your blood pressure has not been adequately controlled by candesartan cilexetil or hydrochlorothiazide administered separately.
2. What you need to know before taking Candacear N
DO NOT take Candaceard H if:
are allergic (hypersensitive) to candesartan cilexetil or hydrochlorothiazide or any of the other ingredients of Candecard H (see section 6);
if you are allergic to sulphonamide preparations. If you are not sure if this applies to you, please ask your doctor.
have severe liver disease or biliary obstruction (problems with gallbladder drainage);
have severe kidney disease;
you are pregnant for more than 3 months. (It is also good to avoid taking Kandeckard H during and during early pregnancy - see the pregnancy point);
you've ever had gout;
you have a persistently high level of calcium in the blood (hypercalcemia);
if you suffer from diabetes or if you have kidney function and you are being treated with a blood pressure lowering medication containing aliskiren.
If you are not sure if any of the above applies to you, talk to your doctor or pharmacist before taking Candacear N.
Warnings and precautions
Talk to your doctor or pharmacist before taking Candecard H if:
you have problems with the heart, liver or kidneys;
you have recently had a kidney transplant;
vomit, have recently had severe vomiting or have diarrhea;
you have adrenal gland disease called Horse Syndrome (or even primary hyperaldosteronism);
suffer from diabetes;
you have ever had a disease called systemic lupus erythematosus (SLE);
you have low blood pressure;
You've ever been hit;
you have ever suffered from allergy or asthma;
if you are taking any of the following medicines used to treat high blood pressure:
ACE inhibitor (eg enalapril, lisinopril, ramipril) and especially if you have kidney disease associated with diabetes;
you think you are (or may become) pregnant. Canadecard H is not recommended in early pregnancy and should not be taken if you are more than 3 months pregnant, as it may cause serious harm to your baby if taken at this stage (see Pregnancy section).
Your doctor may check your kidney function, blood pressure and the amount of electrolytes (eg potassium) in the blood at regular intervals. See also the information under "Do not take Canadian H".
If you are going to have an operative intervention, tell your doctor or dentist that you are taking Kandeckard H. This is necessary because CANDIDADE H in combination with some anesthetics may cause a fall in blood pressure.
Cancer Card H can cause increased skin sensitivity to sunlight.
Children and adolescents
There is a lack of experience in the use of Candardard H in children (under 18 years of age). Therefore, CANDIDADE H should not be used in children.
Ask your doctor if you are an athlete and you are going to have a doping test because Candecard H contains a substance that can lead to positive test results.
Other Drugs and Candideard H
Please tell your doctor or pharmacist if you use or have recently used any other medicines, including medicines obtained without a prescription. CANDIDADE H can affect the way some medicines work, and other medicines may have an effect on Candecard H. If you are using certain medicines, your doctor may decide that blood tests should be made at a certain time.
Your doctor may find it necessary to change the dose and / or take other precautions if you are taking:
ACE inhibitor or aliskiren (see also the information under "Do not take Candiceard H" and "Warnings and Precautions");
Other medicines that help lower blood pressure, including beta-blockers and diazoxide;
Drugs that control heart rhythm (antiarrhythmic drugs) such as digoxin and beta-blockers;
Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen, naproxen, diclofenac, celecoxib or etoricoxib (medicines to relieve pain and inflammation);
Acetylsalicylic acid (if you take more than 3 g per day) (medication
Important information about some of the ingredients of Candecard H
Candecard H contains lactose, ie a type of sugar. If you are informed that you have an intolerance to some sugars, talk to your doctor before taking this medicine.
3. How to take Candeckard H.
Always take Candacear N exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist. It is important to take Canadian H regularly every day.
The usual dose of Canadian H is one tablet a day.
Swallow the tablet with a small amount of water.
It is good to take the tablet every day at the same time. This will help you not miss a reception.
If you take more Candecard H than you should
If you take more Candecard H than your doctor prescribed, contact a doctor or pharmacist for advice immediately.
If you forget to take Candecard H
Do not take a double dose to make up for the missed tablet. Just take the next dose as usual.
If you stop taking Candecard H
If you stop taking Candacear H, your blood pressure may rise again.
Therefore, do not stop taking Candecard H unless you have discussed this first with your doctor
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, Candecard H can cause side effects, although not everybody gets them. It is important to know what these side effects may be. Some of the side effects are caused by candesartan cilexetil and others by hydrochlorothiazide.
Stop taking Kandeartar H and seek immediate medical attention if you have any of the following allergic reactions:
difficulty in breathing, with or without swelling of the face, lips, tongue or throat;
swelling of the face, lips, tongue and / or throat which may cause difficulty in swallowing;
intense itching on the skin (with raised nodules).
Cancer Card H can cause a decrease in the number of white blood cells. Your resistance to infections may be reduced and you may notice tiredness, soreness or fever. If this happens, contact your doctor. Your doctor may occasionally appoint blood tests to check whether Candecard H has an effect on blood count (agranulocytosis).
Other possible side effects include:
Common (affects 1 to 10 patients in 100):
Change in blood count:
Reduced sodium in the blood. If the decrease is significant, you may complain of weakness, loss of energy or muscle cramps;
Increased or decreased potassium in the blood, especially if you have already existing kidney problems or heart failure. If change is significant, you may notice tiredness, weakness, irregular heartbeat or numbness and tingling;
Elevated cholesterol, sugar or uric acid in the blood;
Sugar in the urine;
Feeling dizzy / vertigo or weakness;
Infections of the respiratory tract.
Uncommon (affects less than 1 patient in 100):
Low blood pressure. This may make you feel faint or dizzy;
Loss of appetite, diarrhea, constipation, stomach irritation;
Skin rash, protruding rash (urticaria), rash caused by sensitivity to sunlight.
Rare (affects less than 1 patient in 1,000):
Jaundice (yellowing of the skin and white eyes). If this happens, contact your doctor immediately;
Effects on kidney function, especially if you have kidney problems or heart failure;
Difficulty falling asleep, depression, restlessness;
Numbness or tingling of the hands or feet;
Difficulty breathing (including inflammation or fluid in the lungs);
Elevated temperature (fever);
Inflammation of the pancreas. This can cause moderate to severe stomach pains;
Damage to blood vessels causing red or violet dots on the skin;
Reduced number of red or white blood cells or blood platelets. You may notice tiredness, inflammation, fever or bruising;
Severe rash, which develops rapidly, with bubbles and peeling of the skin, and sometimes with bubbles in the mouth;
Deterioration of existing lupus erythematosus-like reactions or unusual skin reactions.
Very rare (affects less than 1 patient in 10,000):
Swelling of the face, lips, tongue and / or throat;
Back pain, joints and muscles;
Change in hepatic function, including liver inflammation (hepatitis). You may notice fatigue, yellowing of the skin and white eyes, and flu-like symptoms;
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
5. How to store Candecard H
Keep out of the reach and sight of children.
Do not use Candecard H
Packaging content and additional information
What Candecard H contains
The active substances are: candesartan cilexetil and hydrochlorothiazide.
Each tablet contains 8 mg of candesartan cilexetil and 12.5 mg of hydrochlorothiazide.
The other ingredients are:
Lactose monohydrate (see section 2);
What KandeCard H looks like and what the package contains
White, oval, biconvex tablet, scored on both sides.
The divider is only for ease of breaking, for easier swallowing, not for splitting in equal doses.
Al / Al blister with desiccant: 7, 10, 14, 20, 21, 28, 30, 50, 56, 60, 84, 90, 98, 100 tablets.
Al / Al single dose perforation blister with desiccant: 50 x 1 tablets.
HDPE bottle with polypropylene stopper and dryer: 7, 14, 21, 28, 56, 84, 98, 100, 250 tablets.
Not all pack sizes may be marketed.
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