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MILURIT 100 mg. 50 tablets

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What is Milurit and what to use
Milurit tablets contain a drug called allopurinol. Its action is expressed in slowing the rate of chemical reactions in the body.

Milurit is used:
for prevention of gout. This is a disease in which the body produces too much of a substance called uric acid ". Uric acid accumulates in the joints and tendons in the form of crystals. These crystals can cause inflammatory reactions. When inflammation skin around some joints swell, become painful and sensitive to the slightest touch. In addition, there may also be severe pain at these joints;
for the prevention of other conditions under which there is an accumulation of uric acid in the body. These include kidney stones and some other types of kidney problems or when you run the treatment against cancer.
2. What you need to know before you take Milurit
Do not take Milurit:
If you are allergic to allopurinol or any of the other ingredients of this medication (listed in section 6).
Warnings and precautions
Talk to your doctor or pharmacist before taking Milurit:
If you have problems with the liver or kidney. Your doctor may prescribe you a lower dose or to ask you to take the medicine less often than every day. In addition, your doctor will monitor you more closely;
If you have heart problems or high blood pressure;
If you currently have an attack of gout;
If your doctor has told you that you have a lactose intolerance. Milurit tablets contain a small amount of lactose. If your doctor has told you that you have an intolerance to some sugars, contact a doctor before taking this medicinal product.
There are reports of serious skin rashes (hypersensitivity syndrome, Stevens-Johnson Syndrome, toxic epidermal nekroliza) associated with the use of allopurinol. Often, the rash may be with ulcers in the mouth, throat, nose, genitals and conjunctivitis (red or swollen eyes). These potentially life-threatening, serious skin rashes is often accompanied by flu-like symptoms, such as fever, headache, body aches (flu like symptoms). The rash may progress to widespread blistering and peeling of the skin. These serious skin reactions can be more common in people of Chinese or Thai origin.
If you get a rash or skin symptoms, stop taking the Milurit, contact urgently a doctor and say that you are taking this medicine. If you get serious skin rashes, hypersensitivity syndrome, Stevens-Johnson Syndrome or toxic epidermal nekroliza during the use of Milurit, you should never accept Milurit again.
In elderly patients with normal renal and hepatic function Milurit usually proves to be the same effect as in younger patients, but nevertheless recommended intake to the lowest effective dose, which is suitable for them.
To monitor the safety and efficacy of treatment with Milurit, your doctor may decide to make one or more laboratory tests. Please do your research and be sure to display the results of your doctor.

Children and adolescents
Milurit should not be applied to children, except in the case of illness or tumorno in the treatment of enzyme disorders.

Other drugs and Milurit
Inform your doctor or pharmacist if you are taking, you have recently taken or may take any of the following:
acetylsalicylic acid;
Theophylline used to breathing problems;
drugs used for seizures (epilepsy);
antibiotics;
didanozin, which is used for the treatment of HIV infection;
drugs for the treatment of cancer;
medications to lower the immune response (imunopotiskaŝi);
drugs for the treatment of diabetes;
drugs used for heart problems or high blood pressure, for example. ACE inhibitors or drainage tablets (diuretics);
blood thinning medications (anticoagulants), such as. warfarin;
any other medications for the treatment of gout.
Inform your doctor or pharmacist if you are taking or have recently taken any other medicines. This includes medicines obtained without a prescription. herbal medicines as Milurit can affect the action of certain drugs. In addition, other medications may also affect the operation of the Milurit.

Milurit with food and drinks
Take Milirut with food and water.

Pregnancy, lactation
If you are pregnant or breastfeeding, you think you may be pregnant or planning pregnancy, ask your doctor or pharmacist before taking this medication.

Driving and operating machinery
It is possible to feel relaxed, dizzy, or have problems with coordination. In such a case, do not drive and do not operate tools or machinery.

Milurit contains 50 mg lactose.
If your doctor has told you that you have an intolerance to some sugars, ask him, before taking this medicinal product.
How to take Milurit
Always take this medicine exactly as you told Your doctor or pharmacist. If you are unsure of something, ask your doctor or pharmacist.

The recommended doses are as follows:
Swallow the tablets with water.
Take during or immediately after a meal.
Children (under 15 years):
The usual dose is between 100 and 400 mg each day.
Adults (over 18 years):
The usual dose is between 100 and 900 mg every day.
Usually at the beginning starting with a dose of 100 to 300 mg daily.
The elderly (over 65 years old):
Your doctor will prescribe the lowest dose at which Milurit achieves the best control of your symptoms.
If you have a serious problem with the kidneys:
It may be necessary to take 100 mg every day;
or, it may be necessary to take 100 mg at intervals longer than one day.
If you perform dialysis two or three times a week, your doctor may prescribe a dose of 300 or 400 mg to take immediately after dialysis.

If you take more than the required dose Milurit
If you take more than the required dose Milurit, immediately call your doctor or go to hospital. Take the package of the medicine with you.

If you forget to take Milurit
If you forget to take a dose, take it as soon as you remember.
However, if nabližilo is time for the next dose, do not take the missed dose.
Do not take a double dose to make up for a missed dose.

If you have any further questions related to the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects
Like all drugs, this medication can cause side effects, although not everybody gets them.

Stop taking the Milurit and call your doctor immediately if you experience:
unexpected skin reaction (perhaps accompanied by fever, swollen lymph nodes, joint pain, unusual blistering or bleeding, kidney problems or sudden onset of seizures).
The most common adverse reaction to allopurinol intake are skin rashes (affecting less than one person in 10, but more than 1 in 100).

Allergic reactions (affecting less than 1 in 10,000 users)
If you have an allergic reaction, stop taking allopurinol and visit a doctor right away.
Signs may include:
skin rash, skin peeling, irritation of the lips and mouth;
swelling of the face, hands, lips, tongue or throat;
difficulty swallowing or breathing;
very rare signs may have sudden onset of wheezing, palpitations or tightness in the chest and collapse.
Do not take more tablets than if this is recommended by your doctor.

If you receive one of the following complaints on treatment with Milurit, stop taking the tablets and call your doctor as soon as possible.
Reported are the following uncommon side effects (affecting less than one user of 100, but more than one in 1,000):
nausea, vomiting (very rare, with the presence of blood) and diarrhea;
symptoms of allergic reactions, including an itchy rash;
elevated values in research on liver function.
Reported the following side effects are rare (affecting less than one person per 1 000, but more than one in 10 000):
joint pain or painful swelling of the groin, his armpit or neck wells;
jaundice (yellowing of the skin and whites of the eyes);
can affect the function of liver or kidney;
the formation of stones in the urinary tract, the symptoms of which include blood in the urine and pain in the abdomen, waist, or groin;
fever and chills, headache, muscle pain (flu-like symptoms) and general malaise;
any skin changes, such as sores in the mouth, throat, nose, genitals and conjunctivitis (red or swollen eyes), widespread blistering or peeling skin;
serious hypersensitivity reactions, including fever, skin rash, joint pains, abnormal blood tests and results in liver function tests (these may be signs of a poliorganno violation).
Reported are the following very rare side effects (affecting less than 1 in 10,000 users):
high temperature;
presence of blood in the urine;
a change in the normal rhythm of the bowel movement or unusually bad odor of feces;
high level of fats in the blood;
a sense of malaise;
weakness, numbness, instability of the feet, inability to move muscles (paralysis) or loss of consciousness, tingling;
convulsions, seizures or depressed mood;
headache, dizziness, drowsiness or impaired vision;
chest pain, high blood pressure or slow pulse;
fluid retention, which leads to swelling of the ankles, mostly;
sterility in men or inability to obtain or retain an erection or ejaculation during sleep ("wet dreams");
breast enlargement in men and women;
changes in taste sensations, inflammation of the mouth;

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