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Parkinson's

Parkinson's disease (PD) is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms generally come on slowly over time. Early in the disease, the most obvious are shaking, rigidity, slowness of movement, and difficulty with walking. Thinking and behavioral problems may also occur. Dementia becomes common in the advanced stages of the disease. Depression and anxiety are also common occurring in more than a third of people with PD. Other symptoms include sensory, sleep, and emotional problems. The main motor symptoms are collectively called "parkinsonism", or a "parkinsonian syndrome".

The cause of Parkinson's disease is generally unknown, but believed to involve both genetic and environmental factors. Those with a family member affected are more likely to get the disease themselves. There is also an increased risk in people exposed to certain pesticides and among those who have had prior head injuries while there is a reduced risk in tobacco smokers and those who drink coffee or tea. The motor symptoms of the disease result from the death of cells in the substantia nigra, a region of the midbrain. This results in not enough dopamine in these areas. The reason for this cell death is poorly understood, but involves the build-up of proteins into Lewy bodies in the neurons. Diagnosis of typical cases is mainly based on symptoms, with tests such as neuroimaging being used to rule out other diseases.

There is no cure for Parkinson's disease. Initial treatment is typically with the antiparkinson medication L-DOPA (levodopa), with dopamine agonists being used once levodopa becomes less effective. As the disease progresses and neurons continue to be lost, these medications become less effective while at the same time they produce a complication marked by involuntary writhing movements. Diet and some forms of rehabilitation have shown some effectiveness at improving symptoms.[6][7] Surgery to place microelectrodes for deep brain stimulation has been used to reduce motor symptoms in severe cases where drugs are ineffective. Evidence for treatments for the non-movement-related symptoms of PD, such as sleep disturbances and emotional problems, is less strong.

In 2013, PD was present in 53 million people and resulted in about 103,000 deaths globally. Parkinson's disease typically occurs in people over the age of 60, of which about one percent are affected.Males are more often affected than females. When it is seen in people before the age of 40 or 50, it is called young onset PD. The average life expectancy following diagnosis is between 7 and 14 years. The disease is named after the English doctor James Parkinson, who published the first detailed description in An Essay on the Shaking Palsy, in 1817.Public awareness campaigns include World Parkinson's Day (on the birthday of James Parkinson, 11 April) and the use of a red tulip as the symbol of the disease. People with parkinsonism who have increased the public's awareness of the condition include actor Michael J. Fox, Olympic cyclist Davis Phinney, and late professional boxer Muhammad Ali.

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Brand: NOVARTIS
What Comtan is and what it is used for Comtan tablets contain entacapone and are used together with levodopa to treat Parkinson's disease. Comtan supports the action of levodopa in relieving the symptoms of Parkinson's disease. Comtan does not reliev..
53.00€
Brand: ACTAVIS
Composition: Active ingredient: Each tablet contains 5 mg of selegiline hydrochloride. Excipients: milk sugar, microcrystalline cellulose, corn starch, povidone K-25 and stearic acid. Indications: Treatment of Parkinson's Disease and Symptomati..
23.00€
Brand: roche
What Madopar is and what it is used for Madopar dispersible tablets are used to treat Parkinson's disease. Madopar dispersible tablets contain the active substance levodopa, an antiparkinsonian drug, and benserazide (in the form of a hydrochloride)..
29.00€
What Neupro is and what it is used for Neupro belongs to a group of medicines called dopamine agonists that stimulate a certain type of dopamine receptor in the brain. Neupro is used to treat: manifestations and symptoms of Restless Legs Syndrom..
116.00€
What Neupro is and what it is used for Neupro belongs to a group of medicines called dopamine agonists that stimulate a certain type of dopamine receptor in the brain. Neupro is used to treat: manifestations and symptoms of Parkinson's disease a..
199.00€
What Neupro is and what it is used for Neupro belongs to a group of medicines called dopamine agonists that stimulate a certain type of dopamine receptor in the brain. Neupro is used to treat: manifestations and symptoms of Parkinson's disease a..
168.00€
Brand: TEVA
WHAT PRAMIPEXOLE IS PRESENTED AND WHAT IT IS USED FOR Pramipexole  belongs to a group of medicinal products known as dopamine agonists that stimulate dopamine receptors in the brain. Stimulation of dopamine receptors causes nerve impulses in th..
23.00€
Brand: ACCORD
What is SAGILIA and what is it used for? SAGILIA is used to treat Parkinson's disease. It can be used alone or together with levodopa (another medicine to treat Parkinson's disease). With Parkinson's disease there is a loss of cells that produce do..
49.00€
Brand: MEDOCHEMIE
What is SAGILIA and what it is used for SAGILIA is used to treat Parkinson's disease. It can be used alone or together with levodopa (another medicine to treat Parkinson's disease). In Parkinson's disease there is a loss of cells that produce dopam..
159.00€
Brand: NOVARTIS
What is Stalevo? Stalevo is a medicine containing three active substances: levodopa, carbidopa and entacapone (levodopa, carbidopa and entacapone). It is available in the form of different types of tablets in seven concentrations containing 50 to 200..
44.00€
Brand: NOVARTIS
What is Stalevo? Stalevo is a medicine containing three active substances: levodopa, carbidopa and entacapone (levodopa, carbidopa and entacapone). It is available in the form of different types of tablets in seven concentrations containing 50 to 200..
57.00€
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