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Zerotromb 100 mg. 30 tablets

Brand: STADA
Product Code: Zerotromb 100 mg. 30 tablets
Availability: In Stock
Product viewed: 97

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What is Zerotromb and what it is used for
Zerothromb is used in:

treatment of unstable angina pectoris - as part of standard therapy;
acute myocardial infarction - as part of standard therapy;
prophylaxis of recurrent myocardial infarction;
after arterial vascular surgery or interventions (after aortocontrol bypass graft, percutaneous transluminal coronary angioplasty);
for the prevention of transient ischemic attacks and cerebral infarction when warning symptoms are observed;
to reduce the risk of primary myocardial infarction in people with cardiovascular risk factors such as diabetes mellitus, hyperlipidemia, hypertension, obesity, smoking, elderly.

2. What you need to know before taking Zerotromb
Do not take Zerotromb:

if you are allergic to acetylsalicylic acid, salicylates or any of the other ingredients of this medicine (listed in section 6);
if you are allergic to other non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs are most commonly used for arthritis, rheumatism or pain;
if you have had an asthmatic attack or swollen face, lips, tongue, throat (a condition known as angioedema) after taking non-steroidal anti-inflammatory drugs;
if you have active stomach or duodenal ulcers;
in hemorrhagic stroke (stroke with hemorrhage in the brain);
if you have a problem with blood clotting;
if you have severe kidney or liver problems;
if you are in the third trimester of pregnancy, you should not take doses higher than 100 mg / day (see section "Pregnancy, breast-feeding and fertility");
if you are taking a medicine called methotrexate (used in cancers or rheumatoid arthritis) at doses higher than 15 mg / week.
Warnings and precautions
Before taking Zerothrom, you should consult a doctor if you suffer from any of the following conditions:

if you have kidney or liver disease;
if you have or have had stomach or small bowel disease;
if you have high blood pressure;
if you suffer from asthma, hives, polyps in the nose, chronic respiratory infections; Zerothrombe may provoke an asthma attack in people with diagnosed asthma;
if you suffer from gout;
if you suffer from a heavy and heavy menstrual cycle.
You should seek medical advice immediately if the symptoms get worse or if you notice severe and / or unexpected side effects such as unusual bleeding symptoms, serious skin reactions or other signs of serious allergy (see section "Possible side effects").
Tell your doctor if you are planning surgery (even mild intervention such as tooth extraction) because acetylsalicylic acid is a medicine used to thin the blood and may be at increased risk of bleeding.
Acetylsalicylic acid can cause Ray syndrome when administered to children. Ray syndrome is a very rare disease that affects the brain and the liver and can be life-threatening. For this reason, Zerothromb should not be used in children below 16 years unless prescribed by a doctor.
You should be careful not to dehydrate (you may feel thirsty or feel dry mouth), as the use of acetylsalicylic acid may cause a slight worsening of renal function.
This medicinal product is not suitable for use as an analgesic or for lowering body temperature.

Other drugs and Zerotromb
If any of the above applies to you, or if you are not sure, ask your doctor or pharmacist.
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Zerotrom affects the effects of:

Anticoagulants (eg coumarin, heparin, clopidogrel);
Immunosuppressants (medicines used to prevent rejection of a transplanted organ - eg ciclosporin and tacrolimus);
Medicines for the treatment of high blood pressure (eg diuretics and ACE inhibitors);
Medicines for the treatment of impaired heart rhythm (eg digoxin);
Medicines for the treatment of manic episodes (lithium);
Non-steroidal anti-inflammatory drugs for the treatment of pain and inflammation (NSAIDs such as ibuprofen or steroids);
Probenecid - a medicine used in gout;
Valproate, phenytoin - medicines to treat epilepsy;
Acetazolamide - a medicine used in glaucoma;
Oral antidiabetic agents (sulphonylureas);
Methotrexate at doses above 15 mg / week;
Selective serotonin re-uptake inhibitors (eg sertraline or paroxetine) - used to treat depression;
hormone replacement therapy with removed or damaged adrenal glands or the pituitary gland; or medicines to treat inflammation, including rheumatic diseases and inflammation of the gut (corticosteroids).
ZeroTrom with food, beverages and alcohol
Alcohol use may increase the risk of gastrointestinal bleeding or prolong bleeding time.

Pregnancy, breastfeeding and fertility
If you are pregnant or are breast-feeding, think you may be pregnant or plan to become pregnant, ask your doctor or pharmacist for advice before taking this medicine. Zerothromb is not recommended during pregnancy unless clearly prescribed by a doctor.
You should not take Zerothrom in the last three months of pregnancy unless instructed to do so by a doctor. In this case, the daily dose should not exceed 100 mg (see section "Do not take Zerothromb"). Higher doses of this medicinal product during late pregnancy can cause serious harm to the mother and child.

If you are breast-feeding, you should not take Zerothrom unless you are prescribed by your doctor. Small amounts of the active substance acetylsalicylic acid and its metabolites pass into breast milk. Since no side effects have been observed in neonates after accidental use, it is usually not necessary to stop breast-feeding. However, with regular intake or high doses, breast-feeding should be discontinued early.

Driving and using machines
Zerothromb has no influence on the ability to drive or use machines.

3. How to take Zerothromb
Always take this medicine exactly as your doctor or pharmacist has told you. If you are not sure, ask your doctor or pharmacist.

Prevention of myocardial infarction:

The recommended dose is 100 mg once a day.
Prophylaxis in stroke, cerebrovascular accident, transient ischemic attack:

The recommended dose is 100 mg once a day.
Prevention of cardiovascular problems in patients with stable or unstable angina (chest pain):

The recommended dose is 100 mg once a day.
Prevention of thrombus formation following certain surgical operations of the heart or blood vessels:

The recommended dose is 100 mg once a day.
The usual dose for long-term treatment is 100 mg (1 tablet) once a day. Higher dose treatment should be prescribed by a physician, and a daily dose of 300 mg should not be exceeded.

Elderly patients
Elderly patients are given the recommended dose in adults. Typically, acetylsalicylic acid should be used with caution in patients who are more prone to side-effects. Treatment should be reassessed at certain time intervals.

Acetylsalicylic acid should not be used in children and adolescents under 16 unless the medicine is prescribed by a doctor (see section "Warnings and Precautions").

Application method
For oral use. Gastro-resistant tablets should be taken whole before a meal and with a sufficient amount of 1/2 cup of water). Because they have a gastro-resistant coating that protects the stomach and intestines from irritation, they should not be crushed, broken or chewed.

If you use more than the required dose of Zerothromb
Seek immediate medical attention if accidentally you (or someone else) have taken more Zerothrom tablets. Show the doctor's pack and / or the other tablets in it. The doctor will determine what measures should be taken depending on the severity of the overdose. Symptoms of moderate overdose include tinnitus, hearing disorder, headache, dizziness, confusion, nausea, vomiting and abdominal pain. Symptoms of severe overdose include fever, hyperventilation, ketosis, respiratory alkalosis, metabolic acidosis, coma, cardiovascular shock, respiratory failure
If you forget to take Zerotromb
If you forget to take a dose, take it as soon as you remember, in order for the medicine to have the expected effect. Take the next regular dose at the usual time.
Do not take a double dose to make up for the missed dose.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everyone gets them.

Contact your doctor immediately if you experience any of the following conditions:

Sudden wheezing, swelling of the lips, face or body, rash, fainting or difficulty in swallowing (severe allergic reaction);
Flushing the skin with blistering or peeling, which may be accompanied by fever and joint pain. This may be erythema multiforme, Stevens-Johnson syndrome or Lyell syndrome;
Unusual bleeding, such as coughing of blood, vomiting blood or urine, or black stools.
Common (may affect 1 in 10 patients):

Increased bleeding tendency.
Uncommon (may affect 1 in 100 patients):

Difficult breathing.
Rare (may affect 1 in 1,000 patients):

Serious bleeding from the stomach or intestine, haemorrhage in the brain; change in the number of blood cells;
Nausea and vomiting;
Spasms in the lower respiratory tract, asthma attacks;
Inflammation of the blood vessels;
Bruising (bruises) with red-purple spots on the skin (skin bleeding);
Severe skin reactions such as rash, known as erythema multiforme and its life-threatening forms - Stevens-Johnson syndrome and Lyell syndrome;
Hypersensitivity reactions, such as swelling of the lips, face and body, or shock;
Unusually heavy or prolonged menstrual cycle.
Side effects not known:

Noise in the ears or hearing loss;
Stomach or small intestine ulcers and perforation;
Prolonged bleeding time;
Impaired renal function;
Impaired hepatic function;
High level of uric acid in the blood.
 How to store Zerothromb
Keep out of the reach and sight of children.
Store below 25 ° C in the original package for moisture protection.
Do not use this medicine after the expiry date which is stated on the carton. The expiry date refers to the last day of that month.
Do not dispose of medicines in the sewage system or in the household waste container. Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment.

6. Package Contents and Additional Information
What contains Zerotromb
The active substance is: acetylsalicylic acid.

The other ingredients (excipients) are:

Tablet core: cellulose microcrystalline type 102, corn starch, silica, colloidal anhydrous, stearic acid;
Film coating: Eudragit L30 D-55 * (methacrylic acid-ethyl acrylate copolymer (1: 1), polysorbate 80, sodium lauryl sulphate), triethyl citrate, talc.
What Zerotrom looks like and what the package contains
White, round, biconvex, gastro-resistant tablets with a diameter of 7.2 mm. The tablets are available in packs of:
Blisters: PVC / Aluminum foil and PVC / PVDC / Aluminum foil. Pack sizes of 10, 20, 28, 30, 50, 56, 60, 90, 100 tablets;
Polyethylene bags with polyethylene caps. Pack sizes of 10, 30, 50, 100 and 500 tablets;
LDPE packaging with polypropylene caps. Pack sizes of 10, 30, 50, 100 and 500 tablets.
Not all pack sizes may be marketed.






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