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What is Adiflox and what is it used for
The name of your medicine is Adiflox. It contains levofloxacin, a broad spectrum antibiotic of the quinolone group. It has a bactericidal effect, stopping the growth of a number of bacteria that cause infections in your body.
Your doctor has prescribed Adiflox for the treatment of any of the following bacterial infections:
lung, respiratory and pneumonia infections;
urinary tract infections, including bladder and kidney;
skin and soft tissue infections.
2. What you need to know before taking Adiflox
Do not take Adiflox and tell your doctor:
If you are allergic (hypersensitive) to levofloxacin or any of the excipients contained in this medicine (see section 6), or are allergic to another quinolone antibiotic (eg ofloxacin, ciprofloxacin). Signs of an allergic reaction may include: rash, swallowing and breathing problems, swelling of the lips, tongue or throat;
If you suffer from epilepsy;
If you have had tendon problems related to quinolone antibiotic treatment;
If you are pregnant, or are likely to be pregnant, or are planning a pregnancy;
If you are breast-feeding, the medicine may harm your baby;
The drug is for adults only and should not be given to children and adolescents during the growth period (under 18 years) as it is at risk of injury.
Do not take this medicine if any of the above applies to you. If you are not sure, talk to your doctor or pharmacist before taking Adiflox.
Warnings and precautions
Talk to your doctor or pharmacist or nurse before taking Adiflox if:
you are 60 years of age or older;
use corticosteroids (see Other Medicines and Adiflox);
have you ever had a seizure (seizure);
you have a previous brain injury (eg stroke or severe brain injury);
have or have had kidney problems;
suffer from glucose-6-phosphate dehydrogenase deficiency - you are more likely to have serious blood problems when taking this medicine;
you have had mental problems;
you have ever had heart problems - caution should be exercised when using this medicine. The risk is increased if you are born or have a family history of prolonged QT interval (seen on an ECG) if you have a blood salt imbalance (especially low levels of potassium and magnesium in the blood) if you have a very slow heart rate (bradycardia). , have a weak heart (heart failure), have had a heart attack if you are a woman or you are elderly, or are taking other medicines that cause ECG changes (see Other Medicines and Adiflox);
you have diabetes;
have or have ever had a liver disease;
you have myasthenia gravis.
If you are not sure if any of the above apply to you, talk to your doctor or pharmacist before taking Adiflox.
Other medicines and Adiflox
Talk to your doctor or pharmacist if you are taking or have recently taken or might take any other medicines.
This is necessary because Adiflox may affect some medicines and other medicines may affect Adiflox.
It is especially important that you talk to your doctor if you are taking any of the following medicines:
Corticosteroids - may increase the likelihood of inflammation or tendon rupture;
Theophylline - used to treat breathing problems. When combined with Adiflox, the problems may get worse, you are more likely to get convulsions;
Warfarin (Vitamin K Antagonists) - Used for blood thinning. When combined with Adiflox, bleeding may increase. Your doctor will prescribe you specific blood counts;
Nonsteroidal anti-inflammatory drugs (NSAIDs) - used to treat pain and inflammation, such as aspirin, fenbufen, ibuprofen, ketoprofen, indomethacin and more. Co-administration with Adiflox increases the risk of seizures;
Cyclosporin - an immune system-suppressing drug used after transplantation. You may get more side effects than ciclosporin, and levofloxacin may prolong the effect of ciclosporin.
Probenecid (anti-gout medication) and cimetidine (anti-ulcer and acid) - reduce the ability of the kidneys to eliminate Adiflox, so special care is needed.
Medicines used to treat cardiac arrest and heart rhythm disorders (antiarrhythmics - quinidine, hydroquinidine, disopyramide, sotalol, dofatilide, ibutilide, amiodarone).
Antidepressants (tricyclic antidepressants - amitriptyline and imipramine).
Drugs for bacterial infections - macrolide antibiotics (erythromycin, azithromycin, clarithromycin). See the section "Take special care with Adiflox".
Do not take Adiflox at the same time as:
Iron-containing medicines (against anemia), nutritional supplement
Adiflox with food, drink and alcohol
Adiflox can be taken during or during meals. Do not drink alcohol during treatment with Adiflox.
Pregnancy, breastfeeding and fertility
Ask your doctor or pharmacist for advice before taking any medicine. Do not take Adiflox if you are pregnant, thinking about becoming pregnant, or thinking you may be pregnant. Do not take Adiflox if you are breast-feeding or planning to breast-feed.
Driving and using machines
After taking Adiflox, it is possible to get side effects, for example. dizziness, drowsiness, dizziness, changes in vision and more. These side effects can change your ability to concentrate and control the speed of your reaction. Therefore, it is contraindicated to drive or exercise caution if you have experienced any of the side effects described above while taking Adiflox.
3. How to take Adiflox
Always take Adiflox exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist.
Adiflox film-coated tablets should be swallowed whole with sufficient amount of liquid. The prescribed dose should be taken at regular intervals of 12 to 24 hours. The tablets can be taken during or between two meals.
Avoid exposure to direct sunlight
While taking Adiflox and two days after treatment, avoid sun exposure and take precautions to wear - wear a hat, use sunscreen as it increases the risk of your skin turning red, getting a rash.
If you are already taking tablets containing iron, supplements containing zinc, antacids, didanosine or sucralfate
Do not take these medicines at the same time as Adiflox. Take Adiflox at least 2 hours before or 2 hours after taking these medicines, thus avoiding the possibility of reducing the effect of levofloxacin.
How many tablets of Adiflox to take
Your doctor will decide how many Adiflox tablets you need to take.
The dose is determined by the location and type of infection in your body.
The duration of treatment depends on the severity of the infection.
If you feel that the effect of the medicine is too weak or too strong, talk to your doctor and do not change the dose yourself.
Adults and the elderly
Sinus infection - 500 mg once a day.
Lung infection in people with prolonged breathing problems - 500 mg once a day.
Pneumonia - 500 mg once or twice a day.
Urinary tract infection, including bladder and kidney - 250 mg or 500 mg daily.
Prostate infection - 500 mg once a day.
Skin and soft tissue infection - 500 mg once or twice a day.
Adults and the elderly with impaired renal function
Since Adiflox is mainly excreted by the kidneys, your doctor may need to give you a lower dose. Follow your doctor's instructions.
Children and adolescents
Adiflox should not be given to children and adolescents.
If you take more Adiflox than you should
If you accidentally take more tablets than prescribed, tell your doctor or go to the nearest healthcare facility. Take the medicine pack to show it to the doctor. You may experience the following side effects: confusion, dizziness, dizziness, convulsions, nausea, palpitations.
If you forget to take Adiflox
If you forget to take a dose, take it as soon as you remember, unless it is time to take the next dose. In this case, just continue to take Adiflox at the usual time. Do not take a double dose to make up for a missed dose.
If you stop taking Adiflox
Do not stop taking Adiflox because you are feeling better. The course of treatment prescribed by your doctor must be completed so as not to impair its effectiveness. If you stop treatment too soon, the infection is likely to recover, your condition worsens, or the bacteria becomes resistant to the drug.
If you have any further questions on the use of Adiflox, please ask your doctor or pharmacist for advice.
4. Possible side effects
Like all medicines, Adiflox can cause side effects, although not everybody gets them. These reactions are usually mild and disappear within a short period of time.
The frequency of adverse reactions is categorized as:
Very common (may affect more than 1/10 levofloxacin-treated patients);
Common (affects up to 1/10 patients);
Uncommon (affects up to 1/100 patients);
Rare (affecting up to 1/1000 patients);
Very rare (affected up to 1 / 10,000);
Unknown frequency (Frequency cannot be calculated from available data).
Stop taking Adiflox and tell your doctor immediately or go to the nearest hospital if you get any of the symptoms of a serious allergic
Other possible side effects:
Decrease in the number of red blood cells, which can lead to pale skin, yellowing, weakness, shortness of breath (anemia) or decrease in the number of all types of blood cells (pancytopenia).
Drastic decrease in white blood cell count (agranulocytosis) leading to constant recurrence of fever: fever, painful swallowing, feeling unwell, sore throat that does not go away.
Sharp blood circulation disorder (shock similar to anaphylactic shock).
In people with diabetes, an increase in blood sugar (hyperglycaemia) or a decrease in blood sugar (hypoglycaemia).
Movement and gait disorders, muscle coordination (dyskinesia, extrapyramidal disorders).
Smell, loss of smell or taste (parosmia, anosmia, aegeusia).
Temporary loss of consciousness or seizure (syncope).
Temporary vision loss.
Hearing impairment or loss.
Unusually fast, uneven, life-threatening, heart rhythm (impaired cardiac function), including cardiac arrest, deviation in cardiac rhythm (called prolongation of QT interval seen on ECG, electrical activity of the heart).
Difficulty breathing, wheezing, shortness of breath (bronchospasm).
Pulmonary allergic reactions - inflammation, fever, shortness of breath, cough.
Liver inflammation (hepatitis).
Increased skin sensitivity to sun or ultraviolet light (photosensitivity).
Allergic inflammation of the small blood vessels (allergic vasculitis).
Inflammation of the tissues of the mouth (stomatitis).
Muscle tearing or breakage, expressed as severe pain, tension, weakness or muscle cramps (rhabdomyolysis).
Redness and swelling of the joints (arthritis).
Pain, including back, chest or limb pain.
Exacerbation of porphyria for people suffering from porphyria (a very rare metabolic disease).
Prolonged headache with or without blurred vision (benign intracranial hypertension)
If you get any side effects, talk to your doctor or pharmacist. This includes all possible side effects not listed in this leaflet.
5. How to store Adiflox
Do not store above 25 ° C.
Keep out of the reach and sight of children.
Do not use Adiflox after the expiry date which is stated on the carton and blister.
Do not dispose of medicines in sewage or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. Contents of the pack and other information
What Adiflox contains
The active substance is levofloxacin. Each tablet contains 500 mg of levofloxacin.
The other ingredients are:
Tablet core: microcrystalline cellulose, hypromellose, crospovidone, silicified microcrystalline cellulose, sodium stearyl fumarate, silica, colloidal anhydrous.
Film coating: talc, titanium dioxide (E171), macrogol, polyvinyl alcohol, sunshine yellow (E110), tartrazine (E 102), soy lecithin.
What Adiflox looks like and contents of the pack:
Adiflox is a film-coated tablet for oral administration.
The tablets are round, biconvex, orange-coated film-coated tablets.
7 film-coated tablets are packaged in a blister pack of PVDC / Al film.
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