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What is Advantan Ointment and what is it used for
Advantan ointment is an anti-inflammatory drug (corticosteroid) for use on the skin. It suppresses inflammatory and allergic skin reactions and relieves symptoms caused by skin problems such as redness (erythema), thickening of the skin, dullness of the skin, fluid retention (edema), itching and other complaints (burning or pain).
Advantane ointment is used to treat endogenous eczema (atopic dermatitis, neurodermatitis), eczema in children, contact eczema, degenerative, dyshydrotic, numeral eczema or unclassified eczema.
Advantan is available in two different dosage forms, which are of great importance for its therapeutic effect.
2. What you need to know before using Advantan Ointment
Do not use Advantan Ointment
if you are allergic to methylprednisolone aceponate or any of the other ingredients of this medicine (listed in section 6)
if you suffer from tuberculosis or syphilis in the treatment area, viral diseases (eg, measles / chicken pox, herpes), rosacea, periodic dermatitis, ulcers, acne vulgaris, atrophic skin diseases or after-skin reactions in the treated area.
bacterial and fungal diseases of the skin.
Warnings and precautions
Talk to your doctor or pharmacist before using Advantan Ointment
If your doctor thinks that your skin condition is accompanied by a bacterial or fungal infection. Additional specific therapy is needed.
If you apply Advantan ointment on your face, you should avoid eye contact.
If you are using Advantan Ointment you should avoid contact with deep open wounds and mucous membranes.
If you suffer from glaucoma, tell your doctor.
Local skin infections may be exacerbated by topical glucocorticoid treatment.
Glucocorticoids should only be used at the lowest possible dose, especially in children, and only for as long as is absolutely necessary to achieve and maintain the desired therapeutic effect.
It is known from the systemic administration of corticoids that glaucoma may develop with the use of topical corticoids (eg, after a high dose or prolonged use, occlusive dressings, or the application of skin around the eyes).
The prolonged use of topical corticosteroids on vast areas of the body, and especially in occlusion, significantly increases the risk of side effects. Diapers, as well as intertriginal areas, can create occlusive conditions.
No impairment of adrenal function in children was observed when Advantan 0.1% ointment was applied over a large area (40-90% of the skin surface) with non-exclusive treatment. When treating large areas of the skin, the duration of treatment should be as short as possible and the possibility of absorption or systemic effect cannot be completely ruled out.
Contact your doctor if you have blurred vision or other visual disturbances.
Children and adolescents
Advantane ointment should not be used under occlusive conditions. Keep in mind that diapers can create occlusive conditions.
Other medicines and Advantan ointment
Please tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
Pregnancy, breastfeeding and fertility
If you are pregnant or breast-feeding, think you may be pregnant or are planning to become pregnant, ask your doctor or pharmacist for advice before using this medicine.
There are no adequate data from the use of Advantan ointment in pregnant women.
If you are pregnant, your doctor will decide whether to prescribe Advantan Ointment, so please inform him or her. As a general rule, topical products containing corticosteroids should not be administered during the first three months of pregnancy. A number of epidemiological studies suggest that there may be an increased risk of oral clefts among newborns from women who have been treated with glucocorticoids during the first trimester of pregnancy. Particular treatment of large areas, prolonged use or occlusive dressings should be avoided.
It is unknown whether methylprednisolone aceponate is excreted in human milk. It is unknown whether locally administered Advantan ointment can lead to systemic release of methylprednisolone aceponate to detectable amounts in human breast milk.
If you are breast-feeding, you should not apply Advantan ointment on your breast. Your doctor will decide whether to prescribe Advantan ointment if you are breast-feeding, so you should inform him or her about the treatment of large areas, prolonged use or occlusive dressings should be avoided.
No information is available on the effect of methylprednisolone aceponate on fertility.
Driving and using machines
Advantan ointment does not affect the ability to drive and use machines.
3. How to use Advantan Ointment
Always use this medicine exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist.
Use in children and adolescents
The safety of Advantan ointment in children less than 4 months of age has not been established.
No dose adjustment is required when Advantan ointment is given to infants, children and adolescents. Generally, the duration of use should not exceed 4 weeks in children.
If you have the impression that the effect of Advantan Ointment is too strong or too weak, tell your doctor or pharmacist.
If you use more Advantan ointment than you should
Risk of single overdose (when administered once over a large skin area) or accidental oral ingestion is not expected.
If you forget to use Advantan Ointment
Do not use a double dose of Advantan Ointment to make up for a forgotten dose. Continue use as directed by your doctor or as instructed in the package leaflet.
If you stop using Advantan Ointment
If you stop using Advantan ointment prematurely, the initial symptoms may reoccur. Please tell your doctor or pharmacist before stopping treatment with Advantan Ointment.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The evaluation of adverse reactions is based on the following frequencies:
very common (> 1/10); common (> 1/100 to <1/10); uncommon (> 1 / 1,000 to <1/100), rare <1 / 10,000 to 1/1000); very rare (<1 / 10,000), with unknown frequency (cannot be estimated from available data)
burning at the application site, itching at the application site
erythema at the application site, dry skin at the application site, blisters at the application site, irritation at the application site, eczema at the application site, peripheral edema, thinning of the skin (atrophy), bleeding spots (ecchymoses) , bacterial skin infection (impetigo), oily skin
With unknown frequency:
acne, red spots (telangiectasia), skin stretch marks, specific inflammation of the skin in the upper lip and chin (perioral dermatitis), skin depigmentation, allergic skin reactions, inflammation of the hair follicles (folliculitis) at the site of application, enhanced hair growth (hyperthyroidism), hypersensitivity to the drug
5. How to store Advantan ointment
Keep out of the reach and sight of children.
Do not store above 25 ° C.
Do not use this medicine after the expiry date which is stated on the tube and carton. The expiry date refers to the last day of that month.
Do not dispose of medicines in sewage or household waste. Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment.
6. Contents of the pack and other information
What Advantan Ointment Contains
The active substance is methylprednisolone aceponate (methylprednisolone aceponate 0.1%)
The other ingredients are: white, soft paraffin; liquid paraffin; white beeswax; dehimuls E, purified water.
What Advantan Ointment looks like and contents of the pack
Tubes of 15 g, 30 g or 50 g.
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