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ATORGEN 20 mg. 30 tablets

Product Code: ATORGEN 20 mg. 30 tablets
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What is Atorgen and what it is used
Atorgen belongs to the group of medicines known as statins, which are intended to regulate the lipids (fats) in the blood.
Atorgen is used for decreasing the amount of lipids known as cholesterol and other fats (triglycerides) in the blood when a diet low in fat and changes in lifestyle alone are insufficient. If you have an increased risk of heart disease, Atordzhen can also be used to reduce this risk even if your cholesterol values are normal.
A standard cholesterol lowering diet should be continued during treatment.

2. What you need to know before taking Atorgen
You should not take Atorgen
if you are allergic to atorvastatin or similar medicines used to lower blood lipids or to any of the excipients of the drug-additional (described in section 6);
if you have, or have had a disease that affects the liver;
if you have a history of unusual abnormalities of liver enzymes;
if you are a woman of childbearing age not using adequate contraception;
if you are pregnant or planning to become pregnant;
if you are breastfeeding.
Talk to your doctor or pharmacist before taking Atordzhen:
If you suffered a stroke or mini-stroke (also called a transient ischemic attack (TIA)) or stroke by bleeding in the brain or have small pockets of fluid in the brain due to previous strokes;
if you have kidney problems;
if you have thyroid with reduced function (hypothyroidism);
if you have had repeated or unexplained muscle pain, personal or family history of muscle problems;
If you have had previous muscular problems during treatment with other lipid-lowering drugs (eg. other statins or fibrates);
if you regularly drink large amounts of alcohol;
if you have a history of liver disease;
if you are over the age of 70 years.
If any of the above applies to you, the baker will order a blood test before and possibly during your treatment with Atorgen to predict the risk of developing side effects affecting the muscles you. The risk of experiencing side effects affecting the muscles etc. rhabdomyolysis may be increased when other drugs are taken at the same time (refer to section 2 "Taking other medicines").
During treatment
If you have diabetes or are at risk of developing diabetes, your doctor will monitor you carefully while being treated with this medicine. It is likely that you are at risk of developing diabetes if you have high levels of sugar and lipids in the blood, if you are overweight and have high blood pressure.
Talk to your doctor while you are taking this medicine if you have severe lung problems, which can include symptoms such as shortness of breath, dry cough, fatigue, weight loss and fever.
Other medicines and Atorgen
Tell your doctor or pharmacist if you are taking, you have recently taken or might take any other medicines, including medicines obtained without a prescription.
Some drugs may povliayat the effect of atorvastatin is possible or their effect can be influenced by atorvastatin. This type of interaction may lead to a lower efficiency of both drugs. On the other hand this may lead to an increased risk or severity of / side effects, including the important muscle condition called rhabdomyolysis described in Section 4:
Drugs used to suppress the immune system, e. cyclosporin.
Some antibiotics or anti-fungal medicines, for example. erythromycin, clarithromycin, telithromycin, ketoconazole, itraconazole, voriconazole, fluconazole, posaconazole, rifampicin, fusidic acid.
Other drugs, lipid lowering agents, e. gemfibrozil, other fibrates, colestipol,
Some calcium antagonists used in angina pectoris or high blood pressure for example. amlodipine, diltiazem, medications to regulate the heartbeat, such as digoxin, verapamid, amiodarone.
Drugs for the treatment of HIV eg. ritonavir, lopinavir, atazanavir, indinavir, darunavir, delavirdine, efavirenz, saquinavir combination of tiprenavir / raytonavir, nelfinavir / fosamprenavir.
Some drugs used to treat liver problems such as hepatitis C, for example. telaprevir, boceprevir.
Other drugs which are known to interact with atorvastatin include ezetimibe (which lowers cholesterol), warfarin (which prevents the formation of thrombi in the blood), oral contraceptives, stiripentol (anticonvulsant drug for epilepsy), cimetidine (used for heartburn and peptic ulcers), phenazone (a painkiller), colchicine (used to treat gout) and antacid (containing aluminum or magnesium, indigestion).
Drugs that can be purchased from a pharmacy without a prescription, herbal medicines containing St. John's wort.
Atorgen drinks and alcohol
Grapefruit Juice:
Do not drink more than 1 to 2 small glasses of grapefruit juice per day because large quantities of grapefruit juice may alter the effect of Atorgen
Avoid taking excessive amounts of alcohol while taking this medicine. For more details, see point 2 '' Warning and Precautions "
Pregnancy and lactation
Atorgen not take if you are pregnant or if you think you are pregnant or are trying to become pregnant. Do not take Atordzhen if you could become pregnant unless they take appropriate contraceptive measures.
Do not take Atorgen if you are breastfeeding.
The safety of atorvastatin in pregnancy and lactation has not yet been proven.
Driving and using machines
No data Atorgen to affect the ability to drive or operate machinery. Do not drive if this medicine affects your ability to drive. Do not operate any tools or machinery if this medication affects your ability to work with them.
Atordzhen contains lactose
If you are informed by a doctor that you have an intolerance to some sugars, please tell your doctor before taking this medicine.

3. How to take Atorgen
Always take this medicine exactly as your doctor has told you. If you're not sure, ask your doctor or pharmacist.
Before starting treatment your doctor will prescribe a diet low in cholesterol, which must follow during treatment with Atorgen
The recommended starting dose in adults and children over 10 years Atordzhen 10 mg once daily. If you need the doctor may increase the dose to dose for you. Your doctor will adjust the dosage at intervals of 4 weeks or more. Atordzhen maximum dose is 80 mg once daily for adults and 20 mg once daily for children.
Tablets should be swallowed whole with water, can be taken at any time of day with or without food. But try to take the tablets at the same time each day.
Your doctor will determine the duration of treatment with Atorgen
Please consult your doctor if you think that the effect of Atorgen is too strong or too weak.
If you take more than the amount Atorgen
If you take more than the amount Atorgen (more than your usual daily dose), contact your doctor or go to the nearest hospital.
If you forget to take Atorgen
If you forget to take a dose, take the next dose at the time. Do not take a double dose to make up for a missed dose.
If you stop taking Atorgen
If you have any further questions on the use of this medicine or wish to stop your treatment, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
In the event that you experience the following serious side effects, stop taking Atorgen and seek consultation with your doctor immediately or seek emergency treatment at the nearest hospital:
Uncommon side effects (may affect up to 1 in 100 patients):
pancreatitis (inflammation of the pancreas, causing severe pain in the stomach, which can reach the back);
hepatitis (inflammation of liver).
Rare side effects (may affect up to 1 in 1000 patients):
serious allergic reactions, the symptoms may include sudden wheeze and chest pain or tightness, swelling of the eyelids, face, lips, mouth, tongue or throat, severe breathing difficulties, collapse;
serious condition with severe swelling and peeling of the skin, blistering of the skin, mouth, tongue, genitals and fever. Skin rash with pink-red spots, mainly on the palms of hands or soles of the feet, which may form blisters;
muscle weakness, cramps or muscle pain, especially if at the same time you feel unwell or have fever, it can cause unusually irreversible damage to the muscles, which can be life-threatening and lead to kidney problems;
biliary obstruction (cholestasis), which may include signs such as coloring in yellow skin or eyes, pain in the right upper abdomen, loss of appetite.
Very rare side effects (may affect up to 1 in 10,000 patients):
You feel pain in the right upper abdomen, bloating, yellow coloring of the skin and eyes, this may be a sign of liver complications. You urgently need to seek the advice of your doctor.
Other possible side effects with Atorgen
Common side effects (may affect up to 1 in 10 patients):
inflammation of the nose, sore throat, nosebleeds;
allergic reactions;
increases in the values of blood sugar (if you are diabetic require careful monitoring of the values of sugar in the blood for a long time), increase in CK;
nausea, constipation, flatulence, gastrointestinal disorder, diarrhea;
joint pain, muscle pain and back pain, muscle spasm;
variation in blood tests, liver function pokazvatsi.
Uncommon side effects (may affect up to 1 in 100 patients):
anorexia (loss of appetite), weight gain, decreases in blood sugar (if you are diabetic require careful monitoring of the values of sugar in the blood for a long time);
nightmares, insomnia;
dizziness, numbness or tingling in fingers and toes, reduced sense of touch or pain, change in taste, memory loss;
blurred vision;
ringing in the ears and / or head;
vomiting, belching, abdominal pain upper and Dol of abdomen;
rash, skin rash and itching, hives, hair loss;
neck pain, muscle weakness;
fatigue, feelings of fatigue, weakness, chest pain, swelling, mainly in the ankles (edema), fever;
positive results for leukocytes in urine.
Rare side effects (may affect up to 1 in 1000 patients):
violation vision;
unexpected bleeding and bruising;
damage to the tendon.
Very rare side effects (may affect up to 1 in 10,000 patients):
hearing loss;
gynecomastia (breast swelling in men);
Possible side effects reported with some statins (medicines of the same group):
Sexual dysfunction;
Breathing problems including persistent cough and / or shortness of breath or fever;
Diabetes: It is likely that if you have high levels of sugars and fats in the blood, if you are overweight and have high blood pressure. Your doctor will monitor you while you are taking this medicine.

5. How to store Atorgen
Keep out of reach of children.
Blisters of OPA / Al / PVC / Al and bottles: Store in the original container to protect from light and moisture.
Blister of Aclar / PVC / Al: Store in the original carton to protect from light and moisture.
Do not use this medicine after the expiry date of EXP (EXP) on the container or bottle label. The expiry date refers to the last day of that month.
Use within 3 months after first opening.
Do not dispose of medications in wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer use. These measures will help to protect the environment.

6. Contents of the pack and other information
What Atorgen
The active substance is atorvastatin (atorvastatin calcium trihydrate).
Each tablet contains 10 mg, 20 mg, 40 mg or 80 mg of atorvastatin as atorvastatin calcium trihydrate.
The other ingredients of Atorgen are: silica colloidal anhydrous sodium carbonate anhydrous, and m and RFC crystalline cellulose, L-arginine, anhydrous lactose, croscarmellose sodium, hydroxypropyl cellulose (E463), and magnesium stearate. The film coating contains polyvinyl alcohol, titanium dioxide (E171), talc, soya lecithin (E322) and xanthan gum (E4I5)
Atordzhen looks like and what the package contains
The film-coated tablets are oval and white. The 10 mg tablets are marked "10" on one side 20 mg tablets are marked "20" tablets of 40 mg are labeled "40" and 80 mg tablets are marked "80". Tablets 20 mg, 40 mg and 80 mg, are scored on the other side, which is only to facilitate breaking for ease of swallowing and not to divide into equal doses.
Atorgen is in a package for tablets neprozrzhachen HDPE, containing 10, 14, 28, 30, 50, 56, 60, 90, 100, 200, 250 and 500 tablets.
Atordzhen is also in blister in a carton containing 10, 14, 28, 30, 50, 56, 60, 84, 90, 98 and 100 tablets or in blister packs with marked days of the week containing 28 tablets in a carton.
Not all pack sizes may be marketed.

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