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What is Incruse and what it is used for
What is Incruse
Incruse contains the active substance, clopidogrel bromide, which belongs to a group of medicines called bronchodilators.
What is Incruse used for?
This medicine is used to treat Chronic Obstructive Pulmonary Disease (COPD) in adults. COPD is a chronic disease where the airways and alveoli in the lungs gradually become clogged or damaged. This leads to difficulty breathing, which is slowly getting worse. Difficult breathing is also complicated by muscle contraction around the airways, which narrows the airways and thus restricts the penetration and exhalation of air from the lungs.
This drug blocks the narrowing of these muscles, making it easier for the lungs to enter and exit. When taken on a regular basis, the medicine can help control difficult breathing and reduce the effects of COPD on your daily activities.
Incruse should not be used to relieve a sudden dyspnea or wheezing.
If you experience such an attack, you should use a fast-acting inhaled medicine (such as salbutamol).
2. What you need to know before using Incruse
Do not use Incruse:
if you are allergic to ciclosacin or any of the other ingredients of this medicine (listed in section 6).
If you think the above applies to you, do not use this medicine before discussing it with your doctor.
Warnings and precautions
Talk to your doctor before using this medicine:
if you have asthma (Do not use Incruse to treat asthma.)
if you have heart problems;
if you have an eye problem called narrow-angle glaucoma;
if you have enlarged prostate, difficulty urinating or clogging the bladder;
if you have severe liver problems.
Talk to your doctor if you think any of the above applies to you.
Breathing problems immediately after administration
If you get chest tightness, cough, wheezing or difficulty breathing immediately after using your inhaler Incruse:
Stop using this medicine and seek immediate medical attention as you may have a serious condition called paradoxical bronchospasm.
Problems with eyes during treatment with Incruse
If you experience pain or discomfort in the eyes, temporary vision blurring, visual auras or color images associated with redness of the eyes during treatment with Incruse:
Stop using this medicine and seek immediate medical attention as these may be signs of a severe seizure of narrow-angle glaucoma.
Children and adolescents
This medicine should not be used in children or adolescents under the age of 18 years.
Other Drugs and Incruse
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
In particular, tell your doctor or pharmacist if you are taking other long-acting medicines similar to this medicine to treat breathing problems, such as tiotropium. Do not take Incruse with these other medicines.
Pregnancy, breastfeeding and fertility
If you are pregnant or breast-feeding, think you may be pregnant or planning to become pregnant, ask your doctor before taking this medicine. You should not use this medicine if you are pregnant unless your doctor tells you to.
It is not known if the ingredients of Incruse can pass into breast milk. If you are breast-feeding, you should consult your doctor before using Incruse.
Driving and using machines
This medicine is unlikely to affect your ability to drive or use machines.
Incruse contains lactose
Check with your doctor before using this medicine if you have been told that you have an intolerance to some sugars.
3. How to use Incruse
Always use this medicine exactly as your doctor has told you. If you are not sure, ask your doctor or pharmacist.
The recommended dose is one inhalation every day at the same time of the day. You should only inhaled once a day because this medicine lasts for 24 hours.
Do not use a higher dose than prescribed by your doctor.
Use Incruse regularly
It is very important to use Incruse every day, just as your doctor told you. This will help you have no symptoms during the day and at night.
Do not use this medicine to relieve a sudden onset of wheezing or wheezing. If you experience such an attack, you should use a fast-acting inhaled medicine (such as salbutamol).
How to use the inhaler
See "Step by step instructions" in this leaflet for full information.
To use Incruse, you inhale the medicine in the lungs through your mouth using the Ellipta inhaler.
If your symptoms do not improve
If the symptoms of COPD (shortness of breath, wheezing, coughing) do not improve or get worse, or if you use more frequent inhaled medicine: contact your doctor as soon as possible.
If you use more than the necessary dose of Incruse
If you accidentally take a higher dose than prescribed, contact your doctor or pharmacist immediately for advice as you may need medical attention. If possible, show them the inhaler, the pack or this leaflet. You may feel that your heart beats faster than usual, you have visual disturbances or dry mouth.
If you forget to accept Incruse
Do not take an extra dose to make up for the missed dose. Take the next dose at the usual time. If you get wheezing or shortness of breath, use a fast-acting inhaled medicine (such as salbutamol) and then seek medical attention.
If you stop applying Incruse
Take this medicine for as long as your doctor has recommended. The medicine will be effective only when you are taking it. Do not stop treatment, even if you feel better unless your doctor advises you because your symptoms may get worse.
If you have any further questions on the use of this medicine, ask your doctor, pharmacist or nurse.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everyone gets them.
Common side effects - these may affect up to 1 in 10 people:
accelerated heart rhythm;
painful and frequent urination (may be signs of urinary tract infection);
infection of the nose and throat;
a feeling of tension or pain in the area of cheeks and forehead (may be signs of sinus inflammation called sinusitis);
Uncommon side effects - these may affect up to 1 in 100 people:
Reporting of side effects
If any of the side effects gets serious, tell your doctor, pharmacist or nurse. This includes all possible side effects not listed in this leaflet. You can also report side effects directly through the national reporting system. As you report side effects, you can contribute to getting more information on the safety of this medicine.
5. How to Store Incruse
Keep out of the reach and sight of children.
Do not use this medicine after the expiry date which is stated on the carton, sachet and inhaler after EXP. The expiry date refers to the last day of that month.
Store in a sealed socket to protect from moisture. The foil coating should not be opened until you are ready for the first application. After opening the socket, the inhaler can be used within 6 weeks of opening the socket. Write the date after which the inhaler should not be used in the space provided on the label. The date should be written immediately after removing the inhaler from the well.
Do not store above 30 ° C.
If stored in a refrigerator, the inhaler should be left at room temperature for at least one hour before use.
Do not dispose of medicines in the sewage system or in the household waste container. Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment.
6. Package Contents and Additional Information
What the Incruse contains
The active substance is: cleansing bromide.
Each single inhalation delivers a delivered dose (the dose that is released from the mouthpiece) of 55 micrograms of skillinium (equivalent to 65 micrograms of cleftinium bromide).
The other ingredients are: lactose monohydrate (see "Incruse contains lactose" in section 2) and magnesium stearate.
What Incruse looks like and what the package contains
The Ellipta inhaler consists of a gray plastic body, a light green mouthpiece cover and a dose counter. It is packaged in a socket made of laminated foil with detachable foil. The nest contains a sachet to reduce moisture in the package.
The active substance is in the form of a white powder in a blister strip placed in the inhalation
What is an inhaler?
When using Incruse for the first time, you do not have to check that the inhaler is working properly. It contains pre-dosed doses and is ready for use immediately.
The inhaler is packaged in a sachet containing a sachet with a desiccant to reduce moisture. Discard the sachet - do not eat or inhale it.
When you remove the inhaler from its box (sealed socket), it will be in the "closed" position. Do not open it until you are ready to inject a dose of the medicine. After opening the nest, type "Use up" the date on the space provided on the inhaler label. "Use up to" the date is 6 weeks after the date of opening the nest. The inhaler should no longer be used after this date. The nest can be discarded after the first opening.
Instructions for use for the inhaler listed below can be used for the 30-dose or 7-dose inhaler.
Read this before you start
If the inhaler lid opens and closes without inhaled drug, the dose will be lost.
The lost dose will be retained inside the inhaler but will no longer be inhaled.
It is by accident not possible to take more than the necessary medicine or a double dose with one inhalation.
It shows how many doses of medicine have remained in the inhaler.
Before the inhaler was used, the counter showed exactly 30 doses.
It counts 1 less every time you open the lid.
When less than 10 doses are left, half of the counter shows red. After using the last dose, half of the counter shows red and the figure is 0. Your inhaler is now empty.
If you then open the inhaler lid, the dose counter will change from half red to full red.
Each time you open it, you prepare a dose of the medicine.
1) Preparation of a single dose
Open the lid when you are ready to take a dose. Do not shake the inhaler.
Slide the cover down until it clicks.
Now the drug is ready for inhalation.
For confirmation, the dose counter counts with 1 less.
If the counter does not count when a "click" is heard, the inhaler will not release a medicine.
Take it back to your pharmacist and ask him / her.
2) Inhale your medicine
While holding the inhaler away from your mouth, exhale as much as possible. Do not breathe into the inhaler.
Put the mouthpiece between your lips and close them tightly around it. Do not block the air holes with your fingers.
The lips are stuck around the mouthpiece when inhaled.
Do not block the air holes with your fingers.
Inhale continuously, evenly and deeply. Hold your breath as much as possible (at least 3-4 seconds).
Remove the inhaler from your mouth.
Exhale slowly and calmly.
It may not be possible to try the taste or feel the medicine even when using the inhaler properly.
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