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What is quinapril / hydrochlorothiazide aurobindo and what it is used for
Quinapril / hydrochlorothiazide contains medicines called (i) quinapril and (ii) and hydrochlorothiazide. Both medicines lower blood pressure.
(i) Quinapril belongs to a class of medicines known as "ACE Inhibitors." Quinapril helps the blood vessels to relax and thus lowers blood pressure.
(ii) Hydrochlorothiazide belongs to a group of medicines called thiazide diuretics (also known as 'drainage tablets'). Hydrochlorothiazide inhibits the ability of the kidneys to retain fluids and this leads to a decrease in blood pressure.
Quinapril / hydrochlorothiazide is used to treat high blood pressure in patients who are already taking (i) quinapril and (ii) hydrochlorothiazide as separate tablets and who will be facilitated by taking one tablet containing both substances.
2. BEFORE YOU TAKE QUINAPRIL / HYDROCHLOROTIASIDE
Do not take Quinapril / hydrochlorothiazide if:
- you are allergic (hypersensitive) to
other ACE inhibitors
medicines containing sulfonamides
to any of the other ingredients of Quinapril / hydrochlorothiazide Aurobindo.
you have experienced severe allergic reactions to previous ACE inhibitor treatment. These reactions lead to swelling of the face, arms or legs, lips, tongue or throat, causing difficulty in breathing or swallowing (angioedema),
if you suffer from hereditary or caused swelling of the skin (angioedema) for unknown reasons.
if you have severe liver or kidney problems.
if you have aortic stenosis (narrowing of the main blood vessel coming out of the heart).
If you are more than 3 months pregnant. (It is also good to avoid Quinapril / hydrochlorothiazide Aurobindo early in pregnancy - see section "Pregnancy".)
Take special care with Quinapril / hydrochlorothiazide Aurobindo
Before you take Quinapril / hydrochlorothiazide , tell your doctor if:
• have heart, liver or kidney problems
• you have lost a large amount of body fluids or salts (vomiting, diarrhea, sweating more than usual, a diet with limited salt intake, diuretics (drainage tablets) for a prolonged period of time, or previously performed dialysis
• you have allergies or asthma
• You are about to receive treatment to reduce the sting allergy to bees or wasps (densibilisation).
• you are known to have an obstruction (blockage) at the output of the heart
• you have a collagen vascular disease such as scleroderma or systemic lupus erythematosus
• You are about to receive a treatment called LDL cholesterol elimination apheresis.
• you have diabetes or gout
• you are a woman of childbearing potential, consult your doctor about effective co-reception
• breast-feeding or you will start breast-feeding
You should tell your doctor if you think you are (or may be) pregnant. Quinapril / hydrochlorothiazide is not recommended in early pregnancy and should not be taken if you are more than 3 months pregnant as it may cause serious harm to your baby if used during this period (see section "Pregnancy" ).
More frequent check-ups may be necessary at the start of treatment. Your doctor will decide how often you will be examined. You should not miss these visits, even if you feel well.
If your blood pressure drops too much, you should lie down. You may need medical attention.
Taking other medicines
Please tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.
The action of Quinapril / hydrochlorothiazide may be more influenced or influenced by the following medicines:
• Other medicines that lower blood pressure
• Diuretics (drainage drugs)
• Medicines that lead to increased levels of potassium in the blood:
- blood thinners (eg heparin)
- Potassium supplements or salt substitutes containing potassium
• Lithium used in psychiatric disorders
• Medicines that have a sedative effect, including alcoholic beverages and sleeping pills
• Anti-inflammatory drugs such as hydrocortisone, prednisolone, ADTX
• Non-steroidal anti-inflammatory drugs (eg asphin or ibuprofen)
• Insulin or tablets taken with diabetes that control blood sugar
• Antacids (a drug used in digestion)
• Drugs used during muscle relaxation surgery (eg tubocurarine)
• procainamide and digoxin, used to treat heart problems
• Allopurinol used to treat gout
• Ciclosporin and other medicines used to suppress the immune response
• Medicines used to treat cancer
• Tetracycline antibiotic
Remember to tell your medical professional that you are taking Quinapril / hydrochlorothiazide - This is especially important if you are going to
Driving and using machines
The pills may make you feel dizzy. For this reason, caution should be exercised when driving or operating machinery.
Important information about some of the ingredients of Quinapril / hydrochlorothiazide
Quinapril / hydrochlorothiazide contains lactose (a type of sugar). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicinal product.
3. HOW TO TAKE QUINAPRIL / HYDROCHLOROTIASIDE
Always take Quinapril / hydrochlorothiazide Aurobindo exactly as your doctor has told you. Take the tablet with enough water. If you are not sure, ask your doctor or pharmacist. The usual dose is:
The starting dose is one tablet in the morning. Your doctor may increase the dose if you feel that this dose is not sufficient.
Impaired renal function
Administration of Quinapril / hydrochlorothiazide should be avoided if you have severe renal impairment. Your doctor may prescribe a lower dose in patients with renal impairment. Elderly:
You should use Quinapril / hydrochlorothiazide with caution if you are elderly.
Children and adolescents (under 18 years of age)
Quinapril / hydrochlorothiazide Aurobindo is not recommended for use in children and adolescents.
If you take more Quinapril / hydrochlorothiazide than you should
Contact your doctor or the nearest emergency department immediately. Take the pack and the other tablets with you. The signs and symptoms of quinapril / hydrochlorothiazide Aurobindo overdose include: dizziness and fainting resulting from low blood pressure.
If you forget to take Quinapril / hydrochlorothiazide Aurobindo
If you have consumed a dose, take it as soon as you remember, unless it is almost time for the next one. Do not take a double dose to make up for a forgotten dose.
If you have any further questions on the use of this product, ask your doctor or pharmacist.
If you stop taking Quinapril / hydrochlorothiazide
Do not stop taking Quinapril / hydrochlorothiazide before you ask your doctor first, even if you feel better.
4. POSSIBLE SIDE EFFECTS
Like all medicines, Quinapril / hydrochlorothiazide Aurobindo can cause side effects, although not everybody gets them.
Adverse reactions are listed according to their frequency as follows:
Common affects 1 to 10 in 100 patients
Uncommon affects 1 to 10 in 1,000 patients
Rarely affect 1 to 10 in 10,000 patients
Very rare affect less than 1 in 10,000 patients of unknown frequency
The following side effects are serious and require immediate action if given. You should stop taking Quinapril / hydrochlorothiazide Aurobindo and visit your doctor immediately if the following symptoms occur:
swelling of the face, tongue and breathing tube, which can make breathing extremely difficult
Severe abdominal pain
With unknown frequency:
Anemia causing shortness of breath or pale skin
The occurrence of bleeding or bruising is more common than usual
Increased susceptibility to infections causing fever, sore throat or mouth ulcers
Severe, extensive skin rash with blistering
Sudden allergic reaction with shortness of breath, rash, wheezing and falling blood pressure
The following adverse reactions have also been reported:
A drop in blood pressure on standing that causes dizziness, diminution or seizure
Upper respiratory tract inflammation, cough, viral infection
Nausea, vomiting, diarrhea, indigestion, abdominal pain
Headache, fatigue, weakness
Muscle pain, back pain, chest pain
Changes in the results of some blood tests that indicate kidney function
Urinary tract infections, kidney problems
Retention of fluid causing swelling of tissues
Confusion, anxiety, depression
Development of diabetes. Patients with diabetes may need treatment adjustments.
Tingling (feeling of "needles")
Taste disorders, visual disturbances, tinnitus (tinnitus)
Disturbed or accelerated heart rhythm, palpitations
Lowering blood pressure, seizures
Difficulty in breathing, dry mouth
Skin rash, increased skin sensitivity to light, itching, hair loss
Sexual function violated
Formation of gases
Inflammation of the tongue
Inflammation of the lungs
Inflammation of the blood vessels (vasculitis)
High fever, muscle aches and joints, accompanied by skin problems
With unknown frequency:
Inflammation of the pancreas causing abdominal pain
Liver problems that can cause jaundice (yellowing of the skin and whites of the eyes)
Changes in the results of blood tests that show how the liver works
Increase in cholesterol and triglycerides in the blood
If any of the side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist.
5. HOW TO STORE QUINAPRIL
Keep out of the reach and sight of children.
Do not use Quinapril / hydrochlorothiazide after the expiry date which is stated on the carton and blister after EXP. The expiry date refers to the last day of that month.
Store below 25 ° C.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. ADDITIONAL INFORMATION
What Quimapril / chloro-chlorothiazide contains
The active substances are: quinapril (such as quinapril hybrids) and hydrochlorothiazide.
Quinapril / hydrochlorothiazide 10 mg / 12.5 mg film-coated tablets contains 10 mg quinapril equivalent to 10.83 mg quinapril hydrochloride and 12.5 mg hydrochlorothiazide.
Quinapril / hydrochlorothiazide Aurobindo 20 mg / 12.5 mg film-coated tablets contains 20 mg quinapril equivalent to 21.66 mg quinapril hydrochloride and 12.5 mg hydrochlorothiazide.
Quinapril / hydrochlorothiazide Aurobindo 20 mg / 25 mg film-coated tablets contains 20 mg quinapril equivalent to 21.66 mg quinapril hydrochloride and 25 mg hydrochlorothiazide
The other ingredients are:
Tablet core: lactose monohydrate, magnesium carbonate, heavy, crospovidone (Type A), povidone (K30), magnesium stearate
Tablet cover ("Opadrv pink. Hypromellose, titanium dioxide (E 171), hydroxypropyl cellulose, macrogol 400, ferric oxide, red (E 172), ferric oxide, yellow (E 172).
What Quinapril / hydrochlorothiazide looks like and contents of the pack
10 mg / 12.5 mg:
Pink, delimited, oval, double-convex, film-shaped, embossed embossed "D" on the side with a divisible line and "18" on the other. The dividing line is only for ease of breakage, for easier absorption, and not for splitting in equal doses.
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