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What is Tiapride G.L. and what it is used for
Tiapride G.L. is a drug that affects the central nervous system (the so-called antipsychotic drug). It helps to avoid excessive and uncontrolled movements, such as spasms and tremors.
Tiapride G.L. is used for
in anxious, restless behavior, conditions associated with aggression, symptoms of alcohol withdrawal and in elderly patients
Adults and children over 6 years:
treatment of neurological diseases accompanied by motor disorders
Children over 6 years:
Behavioral disorders such as anxious, restless, aggressive behavior
2. What you need to know before you take Tiapride G.L.
Do not take Tiapride G.L.
if you are allergic to tiapride hydrochloride or any of the ingredients of this medicine (listed in section 6);
if you have a so-called prolactin-dependent tumor or breast cancer
if you have a tumor of the adrenal medulla (called a 'pheochromocytoma');
if you are taking levodopa or other medicines to treat Parkinson's disease;
if you are also taking levodopa or similar so-called dopaminergic medicines (used to treat Parkinson's disease; see section 'Other medicines and Tiapride G.L.').
Warnings and precautions
Talk to your doctor or pharmacist before taking Tiapride G.L.
on the concomitant use of alcohol or centrally acting depressants (see section "Other medicines and Tiapri G.L.") - You should not drink alcohol during treatment with Tiapride G.L.
if you or anyone else in your family has had blood clots, as medicines like these are associated with blood clots.
if you are elderly, as sensitivity to this medicine may be increased in elderly patients. Such patients should take Tiapride G.L. only under the strict supervision of their doctor.
If you suffer from any of the following conditions, you can take Tiapride G.L. only under the direct supervision of your doctor:
severe cardiovascular disease,
In case of unexplained fever, paleness, profuse sweating, changes in blood pressure, confusion, muscle stiffness, you should contact your doctor or emergency department immediately, as this may be a sign of a fatal complication - neuroleptic malignant syndrome. Cases of atypical manifestations such as lack of muscle stiffness or hypertension and mild fever have also been reported.
Children (under 6 years)
The use of Tiapride G.L. in children it has not been sufficiently studied. Therefore, the use of Tiapride requires special care.
Other medicines and Tiapride G.L.
Tell your doctor if you are taking, have recently taken or might take any other medicines.
The use of Tiaprtsd with dopaminergic agonists, with the exception of medicines used to treat Parkinson's disease (cabergoline, quinagolide), is contraindicated (see section 2 "Do not take Tiapride GX.").
Combinations that are contraindicated:
medicines that can cause a dangerous heart rhythm disorder (torsades de pointes):
antiarrhythmic agents of class 1a (quinidine, hydroquinidine, disopyramide), antiarrhythmic agents of class III (amiodarone, sotalol, dofetilide, ibutilide), certain neuroleptics (pimozide, sultopride, pipothiazine, sertindole, veralipimazine, chlorine). , pimozide, haloperidol, droperidol, fluphenazine, pepamperone, flupintixol, zuclopenthixol),
certain antiparasitic drugs (halofantrine, lumefrantrine, pentamycin),
other drugs (IV erythromycin, IV spiramycin, IV vincamine, moxifloxacin. bepridil, cisapride, diphemanil, mizolastine)
Levodopa (used to treat Parkinson's disease) - Your doctor should prescribe the combination of the two drugs with the lowest effective dose.
If you suffer from Parkinson's disease and are being treated with dopaminergic agonists without levodopa (amantadine, apomorphine, bromocriptine, entacapone, lisuride, pergolide, piribedil, pramipexole, ropinirole, selegiline); in treatment with Tiapride G.L. dopaminergic agonists should be gradually reduced and discontinued; dopaminergic agonists can cause or exacerbate psychotic disorders.
Medicinal products containing alcohol, as alcohol enhances the sedative effect.
Combinations that require precautions for use:
drugs that cause a slow heart rhythm - bradycardia (class 1a antiarrhythmic agents, beta-blockers, some
class II antiarrhythmic drugs, certain calcium antagonists, cardiac glycosides, pilocarpine,
beta-blockers used in heart failure (bisoprolol, carvedilol, metoprolol, nebivolol);
potassium-lowering agents (diuretics, potassium-lowering stimulants, laxatives, IV amphotericin B,
Drugs whose interaction with Tiaprid G.L. the following should be taken into account:
Tiapride with alcohol
Avoid the use of alcohol and drugs containing alcohol.
Pregnancy, lactation and fertility
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before taking this medicine.
Taking Tiapride G.L. during pregnancy is allowed only in the case of an explicit prescription from your doctor. Information on the use of Tiapride G.L. during pregnancy is limited. When such drugs were given to pregnant women in doses in extraordinary circumstances, it led to low blood pressure. Newborns of mothers who have used Tiaprid G.L. during pregnancy should be closely monitored. The following symptoms may occur in newborns of mothers who have used Tiapride in the last trimester (last three months of their pregnancy): tremors, stiffness and / or muscle weakness, drowsiness, agitation, respiratory problems and difficulty eating. If your baby develops any of these symptoms, you may need to contact your doctor.
As the active substance tiapride is excreted in breast milk, you must stop breast-feeding before taking Tiapride G.L.
Due to its mechanism of action, the active substance may affect ovulation and your menstrual cycle; in some cases it can also impair fertility.
Driving and using machines
This medicine may impair your reactivity and your ability to drive!
Tiapride G.L. may change your ability to react, as a result of which your ability to actively participate in traffic and work with machines may be impaired. This is especially true if you are also taking alcohol and / or centrally acting depressants (see section "Other medicines and Tiapride G.L.")
3. How to take Tiapride G.L.
Always take this medicine exactly as your doctor has told you. If you are not sure, talk to your doctor or pharmacist.
Your doctor will prescribe a dose that is right for you. The usual dose for long-term treatment is 2 - 4 tablets a day. A higher dose may be needed at the beginning of treatment.
Take the tablets whole, with enough fluids, along with food. The tablets can be divided into equal doses (halves and quarters).
Impaired renal function
Your doctor will prescribe a lower dose that is right for you.
Use in children (under 6 years)
The use of Tiapride in children has not been sufficiently studied. Therefore, the use of Tiapride requires special care.
If you take more Tiapride G.L.
If you take more Tiapride G.L tablets than you need, dizziness and tiredness, dizziness, lethargy, coma, low blood pressure and severe movement problems (so-called Parkinson's syndrome) may occur. If you experience any of these symptoms, tell your doctor.
The doctor's recommendations in case of overdose are contained at the end of this leaflet.
If you forget to take Tiaprvd G.L.
If you forget to take Tiapride, take the dose as soon as you remember. However, do not take the dose if you notice this shortly before or just at the time of the next dose. In this case, follow the instructions as usual, as if nothing had happened. Do not take a double dose to make up for a forgotten dose.
If you stop taking Tiaprid GX.
Do not stop taking Tiapride on your own. Talk to your doctor if you want to stop taking Tiapride.
If you have any further questions on the use of this medicine, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
The following side effects have been reported:
Common (may affect 1 to 10 users in 100)
Dizziness / vertigo, headache, Parkinson's-like symptoms (tremor, high blood pressure, limited movement, and increased salivary secretion Fatigue / dizziness / fatigue, drowsiness, insomnia, sedation, agitation, apathy, weakness
Increased concentration of the hormone prolactin in the blood
Uncommon (may affect 1 to 10 users in 1,000)
Inability to remain still, abnormal tension or muscle contraction leading to cramps or incorrect positions (eg legs, neck, eyes, jaw)
Tiapride G.L. causes an increase in the level of a certain hormone (prolactin) in the body. This can lead to the following side effects: breast milk secretion, amenorrhea (absence of a menstrual cycle), breast pain, breast enlargement and lack of sexual desire in women; enlargement of the mammary glands and impotence in men. These symptoms disappear after stopping treatment with this medicine.
Rare (may affect 1 to 10 users in 10,000)
Acute movement disorders
Aspiration pneumonia caused by food particles or vomiting in the white matter
5. How to store Tiapride GX
Keep out of reach of children.
This medicinal product does not require any special storage conditions.
Do not use this medicine after the expiry date which is stated on the carton. The expiry date refers to the last day of that month.
Do not throw away any medicines via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. Contents of the package and additional information
What Tiapride G.L.
The active substance is tiapride hydrochloride. 1 tablet contains 111.1 mg tiaprid hydrochloride, corresponding to 100 mg tiaprid.
The other ingredients are: mannitol, microcrystalline cellulose, magnesium stearate, povidone, colloidal anhydrous silica
What Tiapride G.L. and what the package contains
Tiapride G.L. are white, round tablets with bevelled edges and two score lines on both sides.
Tiapride G.L. tablets are packed in blister packs of PVC / aluminum 20, 30, 50, 60, 90, 100 and 500 (stack of 10x50) tablets.
Not all pack sizes may be marketed.
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