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VOLUVEN 500 ml.

Brand: BOIRON
Product Code: VOLUVEN 500 ml.
Availability: In Stock
Product viewed: 969

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What VOLUVEN is and what it is used for
VOLUVEN is a volumetric substitute for plasma that is used to restore blood volume in the blood loss when other products called self-administered crystalline solutions are not considered sufficient.
2. What you need to know before using VOLUVEN
Do not use Aquool if:
Are allergic to any of the active substances or any of the other ingredients of this medicine;
You suffer from severe generalized infection (sepsis);
You have burns;
Have kidney damage or have dialysis;
You suffer from bleeding in the brain (intracranial or cerebral bleeding);
You are in critical condition (ie you must remain in an intensive care unit);
You have too much fluid in the body or you are told you have a condition known as hyperhydration;
You have fluid in your lungs (pulmonary edema);
You are dehydrated;
Have been told you have high blood sodium or chlorine in the blood;
Have severely impaired hepatic function;
Have severe heart failure;
You have severe problems with blood clotting;
You have a transplanted organ.
Warnings and precautions
It is important to tell your doctor if you have:
Impairment of liver function;
Heart or circulatory problems;
Bleeding disorders (coagulation);
Kidney problems.
Because of the risk of allergic (anaphylactic / anaphylactoid) reactions, you will be closely monitored for early signs of an allergic reaction when you are taking this medicine.
Operation and trauma
Your doctor will carefully evaluate if this medicine is right for you.
Your doctor will carefully determine the dose of Aquulin to prevent fluid overload. This will be done, especially if you have problems with your lungs or heart or blood circulation. Nursing staff will also take measures to track the water balance, salt balance in your blood and kidney function. You may receive additional salts if necessary.
In addition, it will be ensured that you are getting enough fluids.
Water is contraindicated if you have kidney damage or kidney damage requiring dialysis.
If kidney damage occurs during treatment:
If the doctor finds first signs of kidney damage, he / she will stop giving you this medicine. In addition, your doctor may need to monitor your kidney function for up to 90 days.
If Water is given repeatedly, your doctor will monitor your blood's ability to clot, clotting time and other functions. In case of damage to the ability of your blood to clot, your doctor will stop giving you this medicine.
Applying this solution is not recommended if you are undergoing open heart surgery and you are on a heart-lung device to help pump blood during surgery.
Children
The data in children are limited, so it is recommended that HES-containing products should not be used in this population.
Other medicines and VOLUVEN
Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription. So far, it is not known that Voluvil has any interactions with other drugs.
Water with food and beverages
It is not known to have Voluen to have a negative effect when administered concomitantly with food or beverages.
Pregnancy and breastfeeding
So far, there are no clinical data on the use of Volumen in pregnant women. Animal studies do not indicate a direct or indirect negative effect on pregnancy, embryo / fetal development, parturition or postnatal development. No teratogenic effect was observed.
If you are pregnant, your doctor will only give you an Aquulum once you have assessed the benefits to you in relation to the potential risk to your baby.
To date, there is no clinical data on the use of Volunen during the lactation period.
Driving and using machines
After using Volunaven, your ability to drive or operate machinery will not be affected.
3. How to use Aquarium
Water will be administered to you by or under the direct supervision of your doctor, who will monitor the amount of Volunteer you will be given.
Mode of application
You will receive this medicine by infusion into the veins (via an intravenous system). The rate of infusion, along with the amount of infusion solution, will depend on your specific needs, the illness you are being treated for, and the maximum daily dose.
Dosage
Your doctor will decide which is the right dose for you.
Your doctor will use the lowest possible effective dose and will not give Vollux more than 24 hours.
The maximum daily dose is 30 ml / kg for Aquarium.
Use in children
There is only limited experience with the use of this medicine in children. Therefore, the use of this medicine in children is not recommended.
If you have received more than the required dose of Volunaven
As with all volumetric replacements, if you are given too much water, your bloodstream may become overwhelmed, which may lead to, for example, lung retention (pulmonary edema).
Your doctor will ensure you get the right amount of Water. However, different people need different dosages, and if the dose is too high for you, your doctor may immediately stop VOLUVEN and, if necessary, take a medicine that removes water from the body (diuretic).
If you have any further questions on the use of this product, ask your doctor or pharmacist.
4. Possible side effects
Like all medicines, Volunaven can cause side effects, although not everyone gets them.
Very common: may affect more than 1 in 10 people;
Common: may affect up to 1 in 10 people;
Uncommon: may affect up to 1 in 100 people;
Rare: may affect up to 1 in 1,000 people;
Very rare: may affect up to 1 in 10,000 people;
Not known: can not be estimated from the available data.
Blood and lymphatic system disorders
Rare (may affect up to 1 in 1,000 people):
Upon administration of hydroxyethyl starch, blood clotting disturbances may occur beyond dose-dependent dilution.
Immune system disorders
Rare (may affect up to 1 in 1,000 people):
Medicinal products containing hydroxyethyl starch can lead to severe allergic reactions (skin redness, mild flu-like symptoms, slow or fast heart rhythm, swelling of the throat and difficulty in breathing, fluid in the lungs that is not caused by heart problems).
Skin and subcutaneous tissue disorders
Common (may affect up to 1 in 10 people):
Pruritus is a known side effect of hydroxyethyl starch when used for long periods of time and in high doses.
Research
Common (may affect up to 1 in 10 people):
The serum amylase enzyme level may increase during the use of hydroxyethyl starch and may affect the diagnosis of inflammation of the pancreas (pancreatitis). However, in this case, elevated serum amylase levels should not be considered as diagnostic for pancreatitis.
Other side effects that occur at high doses are related to blood thinning, such as prolonged clotting time.
Not known (can not be estimated from the available data):
Kidney defeat;
Loss of the liver.
How to store VOLUVEN
Keep out of the reach and sight of children. Do not freeze.
Do not use Volaven after the expiry date which is stated on the label. The expiry date refers to the last day of that month.
Your doctor or nurse will make sure that the solution is clear, particle-free, the pack is not damaged and the bag is removed from the freeflex bag before use.
The solution should be used immediately after opening and the remaining unused amount after the infusion should be destroyed. For single use only.
Do not dispose of medicines in the sewer or in the household waste container.
Ask your pharmacist how to dispose of medicines you no longer use. These measures will help to protect the environment.
6. Package Contents and Additional Information
What AquaVol contains
1000 ml infusion solution contains:
The active substances are:
Poly (0-2-hydroxyethyl) starch: 60.00;
Molar substitution: 0.38-0.45;
Average molecular weight: 130,000 Da;
Sodium Chloride: 9.00 g.
Electrolytes:
Na & lt; + & gt;: 154 mmol / l;
Cl-: 154 mmol / l.
Theoretical osmolarity: 308 mosm / l;
Titratable Acidity: <1.0 mmol NaOH / l;
PH: 40-5.5.
The other ingredients are: sodium hydroxide, hydrochloric acid, water for injections.
What Vollumen looks like and contents of the pack
Aquulfen is a sterile, clear to slightly opalescent solution, colorless to pale yellow. It is contained in:
glass bottle;
Flexible bags made of polyolefin (freeflex);
Polyethylene (PE) packaging;
PVC bag.
Type II colorless glass bottles with a halobutyl rubber stopper and an aluminum seal:
1 x 250 ml, 10 x 250 ml 1 x 500 ml, 10 x 500 ml.
Freeflex polyurethane bag with protective film:
1 x 250 ml, 10 x 250 ml, 20 x 250 ml, 30 x 250 ml, 35 x 250 ml, 40 x 250 ml;
Plastic bottles of PE (Bottelpack):
1 x 250 ml, 10 x 250 ml, 20 x 250 ml, 30 x 250 ml;
1 x 500 ml, 10 x 500 ml, 20 x 500 ml.
PVC bag:
1 x 250 ml, 25 x 250 ml;
1 x 500 ml, 15 x 500 ml.
All types of packaging can be marketed.
The following information is intended for medical professionals only:
The use of HES should be limited to the initial phase of resuscitation with a maximum time interval of 24 hours.
The maximum daily dose is 30 ml / kg for VOLUVEN
The lowest effective dose should be used. Treatment should be performed under constant haemodynamic control so that the infusion is discontinued as soon as the haemodynamic endpoints are reached. The recommended maximum daily dose should not be exceeded.
The initial 10-20 ml should be infused slowly and the patient carefully monitored so that any anaphylactic / anaphylactoid reaction can be detected as early as possible.
If an anaphylactoid / anaphylactic reaction occurs, the infusion should be discontinued immediately and appropriate emergency medical treatment initiated.
The duration of treatment depends on:
The low blood volume;
Blood pressure;
Dilution of the blood and its components (platelets, red blood cells, etc.).
Use in children
There is only limited experience with the use of this medicine in children. Therefore, the use of this medicine in children is not recommended.
For single use only.
To be used immediately after opening the container.
The remaining unused quantity is destroyed.
Only be used if the solution is clear, particle-free and container integrity is preserved.
Remove the sheath from the polyolefin (fireeflex) and PVC jacket before use.

 

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